Nanoparticles-mediated delivery of herbal extract: Impact on inhibition advanced glycation end-product (AGEs): A systematic review
This systematic review compiles and analyzes research on the therapeutic efficacy of nanoparticle-mediated delivery systems for herbal extracts aimed at inhibiting the formation of Advanced Glycation End- products. A comprehensive search of PubMed and Google Scholar was conducted in accordance with...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2024-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2024/67/bioconf_icobeaf2024_04005.pdf |
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| _version_ | 1841526738883969024 |
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| author | Astuti Febriana Akrom Mustofa |
| author_facet | Astuti Febriana Akrom Mustofa |
| author_sort | Astuti Febriana |
| collection | DOAJ |
| description | This systematic review compiles and analyzes research on the therapeutic efficacy of nanoparticle-mediated delivery systems for herbal extracts aimed at inhibiting the formation of Advanced Glycation End- products. A comprehensive search of PubMed and Google Scholar was conducted in accordance with the PRISMA systematic review statement guidelines included studies published within the past 10 years. Our examination spans several studies utilizing different nanoparticle formulations—such as gold, silver, and zinc oxide nanoparticles—and encapsulated herbal extracts, including Poria cocos, Nigella sativa, and curcumin, among others. The outcomes indicate that these nanocomplexes not only foster enhanced delivery and bioavailability of the herbal extracts but also significantly decrease inflammatory biomarkers and blood glucose levels, enhance antioxidant responses, and protect against cellular damage caused by oxidative stress. This review emphasizes the potential of nanoparticles to augment the therapeutic properties of herbal medicines for preventing and managing diabetic complications through the inhibition of AGEs formation. |
| format | Article |
| id | doaj-art-431fd8d9980a40ab8e3267b73e8ea5f7 |
| institution | Kabale University |
| issn | 2117-4458 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-431fd8d9980a40ab8e3267b73e8ea5f72025-01-16T11:19:46ZengEDP SciencesBIO Web of Conferences2117-44582024-01-011480400510.1051/bioconf/202414804005bioconf_icobeaf2024_04005Nanoparticles-mediated delivery of herbal extract: Impact on inhibition advanced glycation end-product (AGEs): A systematic reviewAstuti Febriana0Akrom1Mustofa2Study Program of Pharmacy, Politeknik Kesehatan TNI AU Adisutjipto, BantulFaculty of Pharmacy, Universitas Ahmad DahlanFaculty of Pharmacy, Universitas Gadjah MadaThis systematic review compiles and analyzes research on the therapeutic efficacy of nanoparticle-mediated delivery systems for herbal extracts aimed at inhibiting the formation of Advanced Glycation End- products. A comprehensive search of PubMed and Google Scholar was conducted in accordance with the PRISMA systematic review statement guidelines included studies published within the past 10 years. Our examination spans several studies utilizing different nanoparticle formulations—such as gold, silver, and zinc oxide nanoparticles—and encapsulated herbal extracts, including Poria cocos, Nigella sativa, and curcumin, among others. The outcomes indicate that these nanocomplexes not only foster enhanced delivery and bioavailability of the herbal extracts but also significantly decrease inflammatory biomarkers and blood glucose levels, enhance antioxidant responses, and protect against cellular damage caused by oxidative stress. This review emphasizes the potential of nanoparticles to augment the therapeutic properties of herbal medicines for preventing and managing diabetic complications through the inhibition of AGEs formation.https://www.bio-conferences.org/articles/bioconf/pdf/2024/67/bioconf_icobeaf2024_04005.pdf |
| spellingShingle | Astuti Febriana Akrom Mustofa Nanoparticles-mediated delivery of herbal extract: Impact on inhibition advanced glycation end-product (AGEs): A systematic review BIO Web of Conferences |
| title | Nanoparticles-mediated delivery of herbal extract: Impact on inhibition advanced glycation end-product (AGEs): A systematic review |
| title_full | Nanoparticles-mediated delivery of herbal extract: Impact on inhibition advanced glycation end-product (AGEs): A systematic review |
| title_fullStr | Nanoparticles-mediated delivery of herbal extract: Impact on inhibition advanced glycation end-product (AGEs): A systematic review |
| title_full_unstemmed | Nanoparticles-mediated delivery of herbal extract: Impact on inhibition advanced glycation end-product (AGEs): A systematic review |
| title_short | Nanoparticles-mediated delivery of herbal extract: Impact on inhibition advanced glycation end-product (AGEs): A systematic review |
| title_sort | nanoparticles mediated delivery of herbal extract impact on inhibition advanced glycation end product ages a systematic review |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2024/67/bioconf_icobeaf2024_04005.pdf |
| work_keys_str_mv | AT astutifebriana nanoparticlesmediateddeliveryofherbalextractimpactoninhibitionadvancedglycationendproductagesasystematicreview AT akrom nanoparticlesmediateddeliveryofherbalextractimpactoninhibitionadvancedglycationendproductagesasystematicreview AT mustofa nanoparticlesmediateddeliveryofherbalextractimpactoninhibitionadvancedglycationendproductagesasystematicreview |