Dynamic collateral sensitivity profiles highlight opportunities and challenges for optimizing antibiotic treatments.

Dynamic collateral sensitivity profiles highlight opportunities and challenges for optimizing antibiotic treatments.

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As failure rates for traditional antimicrobial therapies escalate, recent focus has shifted to evolution-based therapies to slow resistance. Collateral sensitivity-the increased susceptibility to one drug associated with evolved resistance to a different drug-offers a potentially exploitable evoluti...

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Bibliographic Details
Main Authors: Jeff Maltas, Anh Huynh, Kevin B Wood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002970
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