Construction and experimental verification of a novel nine-glycosylation-related gene prognostic risk model for clear cell renal carcinoma

Construction and experimental verification of a novel nine-glycosylation-related gene prognostic risk model for clear cell renal carcinoma

Objective: Patients with clear cell renal carcinoma (ccRCC) typically have poor prognosis. Glycosylation modification plays an important role in ccRCC. This study aimed to develop a novel signature for predicting ccRCC prognosis based on glycosylation-related genes (GRGs). Methods: Differentially ex...

Full description

Saved in:

Bibliographic Details
Main Authors:	Wanlei Sun, Long Guo, Jianqing Ye, Min Zhou, Cong Shu, Xin Ying, Hongliang Liu, Fei Liu
Format:	Article
Language:	English
Published:	Elsevier 2024-11-01
Series:	Heliyon
Subjects:	Clear cell renal carcinoma Glycosylation modification Prognostic signature Risk model Immune cell infiltration
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024152899
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

PAQR6 as a prognostic biomarker and potential therapeutic target in kidney renal clear cell carcinoma
by: Tao Zou, et al.
Published: (2024-12-01)

Identification and analysis of prognostic ion homeostasis characteristics in kidney renal clear cell carcinoma
by: Xiangmin Zhang, et al.
Published: (2025-01-01)

Identification of small molecule drugs and development of a novel autophagy‐related prognostic signature for kidney renal clear cell carcinoma
by: Qianwei Xing, et al.
Published: (2020-10-01)

Transcriptome-based network analysis related to regulatory T cells infiltration identified RCN1 as a potential biomarker for prognosis in clear cell renal cell carcinoma
by: Yang Qixin, et al.
Published: (2024-11-01)

Comprehensive analysis of heat shock protein 110, 90, 70, 60 families and tumor immune microenvironment characterization in clear cell renal cell carcinoma
by: Wenjing Liao, et al.
Published: (2025-01-01)

MOICS, a novel classier deciphering immune heterogeneity and aid precise management of clear cell renal cell carcinoma at multiomics level
by: Ying Liu, et al.
Published: (2024-12-01)

CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma
by: Kangkang Yang, et al.
Published: (2025-01-01)

Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinoma
by: Yuli Jian, et al.
Published: (2025-02-01)

Bladder Metastasis from Clear Cell Renal Cell Carcinoma: A Case Report
by: İlkin Hamid-Zada, et al.
Published: (2024-07-01)

Identifying ADME-related gene signature for immune landscape and prognosis in KIRC by single-cell and spatial transcriptome analysis
by: Hongyun Wang, et al.
Published: (2025-01-01)

Predictive nomogram for ischemic stroke risk in clear cell renal cell carcinoma patients
by: Jie Wen, et al.
Published: (2024-12-01)

Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma
by: Liuyan Chen, et al.
Published: (2025-01-01)

Integrated RNA sequencing analysis and machine learning identifies a metabolism-related prognostic signature in clear cell renal cell carcinoma
by: Yunxun Liu, et al.
Published: (2025-01-01)

Integrated pan-cancer analysis and experimental verification of the roles of ZBED3 in kidney renal clear cell carcinoma
by: Shaobo Wu, et al.
Published: (2024-11-01)

RSK4 promotes the metastasis of clear cell renal cell carcinoma by activating RUNX1-mediated angiogenesis
by: Jing Ma, et al.
Published: (2025-12-01)

GABPA inhibits tumorigenesis in clear cell renal cell carcinoma by regulating ferroptosis through ACSL4
by: Yaqian Wu, et al.
Published: (2024-11-01)

FOXP3 as a prognostic marker and therapeutic target in immunogenic cell death modulation for clear cell renal cell carcinoma
by: Jian Chen, et al.
Published: (2025-01-01)

The elevated DERL3 expression indicates poor prognosis in renal clear-cell carcinoma
by: Weining Fan, et al.
Published: (2025-01-01)

Case report: Tongue metastasis as an initial sign of clear cell renal cell carcinoma and its prognosis
by: Shuo Liu, et al.
Published: (2025-01-01)

A novel risk model consisting of nine platelet-related gene signatures for predicting prognosis, immune features and drug sensitivity in glioma
by: Sanlin Wei, et al.
Published: (2024-12-01)

CT-based scoring system for diagnosing eosinophilic solid and cystic renal cell carcinoma versus clear cell renal cell carcinoma
by: Sunya Fu, et al.
Published: (2025-01-01)

The predictive value of radiomics and deep learning for synchronous distant metastasis in clear cell renal cell carcinoma
by: Wan-Bin He, et al.
Published: (2025-01-01)

Identification of gasdermin B function in the progression of renal clear cell carcinoma by a pan-cancer analysis
by: Xiangyuan Tan, et al.
Published: (2024-11-01)

The PLCG2 Inhibits Tumor Progression and Mediates Angiogenesis by VEGF Signaling Pathway in Clear Cell Renal Cell Carcinoma
by: Chuanyi Zhao, et al.
Published: (2024-11-01)

Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma
by: Andreea Boiangiu, et al.
Published: (2024-12-01)

Radiomics-based machine learning role in differential diagnosis between small renal oncocytoma and clear cells carcinoma on contrast-enhanced CT: A pilot study
by: Roberto Francischello, et al.
Published: (2024-12-01)

Inflammasome complex genes with clinical relevance suggest potential as therapeutic targets for anti-tumor drugs in clear cell renal cell carcinoma
by: Yin Fengchao, et al.
Published: (2024-11-01)

Tumor-initiating and metastasis-initiating cells of clear-cell renal cell carcinoma
by: Dinh-Xuan Pham, et al.
Published: (2025-02-01)

Pan-cancer landscape of DCTPP1 and preliminary exploration of DCTPP1 in renal clear cell carcinoma
by: Hongze Li, et al.
Published: (2024-11-01)

Machine learning-derived natural killer cell signature predicts prognosis and therapeutic response in clear cell renal cell carcinoma
by: Jinchen Luo, et al.
Published: (2025-01-01)

Comprehensive analysis of lysine lactylation and its potential biological significance in clear cell renal cell carcinoma
by: Bangbei Wan, et al.
Published: (2024-12-01)

Rhomboid-like 2 correlated with TME infiltration inhibits cuproptosis-related genes and drives malignant phenotype in clear cell renal cell carcinoma
by: Zhifei Che, et al.
Published: (2024-11-01)

Predicting first-line VEGFR-TKI resistance and survival in metastatic clear cell renal cell carcinoma using a clinical-radiomic nomogram
by: Yichen Wang, et al.
Published: (2024-11-01)

Atypical Presentation of Rapidly Progressive Cutaneous Metastases of Clear Cell Renal Carcinoma: A Case Report
by: Carmen Andrada Iliescu, et al.
Published: (2024-11-01)

Endogenous peptide CBDP1 inhibits clear cell renal cell carcinoma progression by targeting USP5/YTHDF2/TRPM5 axis
by: Yang Zhang, et al.
Published: (2025-01-01)

Expression pattern of cancer-associated cellular senescence genes in clear cell renal cell carcinoma distinguishes tumor subclasses with clinical implications
by: Zhongxu Zhu, et al.
Published: (2025-01-01)

Dynamic Changes in Serum Immunoglobulin G Predict Clinical Response and Prognosis in Metastatic Clear-cell Renal Cell Carcinoma
by: Honglei Cui, et al.
Published: (2024-12-01)

The 7-Methylguanosine (m7G) methylation METTL1 acts as a potential biomarker of clear cell renal cell carcinoma progression
by: Yi Liu, et al.
Published: (2025-01-01)

Pleural Rosai-Dorfman disease complicated with renal clear cell carcinoma: a case report and literature review
by: Sudan Tang, et al.
Published: (2025-01-01)

PSENEN influences the progression of renal clear cell carcinoma by regulating the immune microenvironment and oxidative phosphorylation
by: Congying Huang, et al.
Published: (2024-11-01)