Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation
<i>Background and Objectives</i>: Studies have shown that inflammation markers can be used as prognostic tools in predicting acute ischemic stroke. In this study, we conducted a comparison of several inflammation scores in predicting left atrial thrombosis (LAT) in patients with ischemic...
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2024-12-01
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| author | Vedat Cicek Sahhan Kilic Selami Dogan Almina Erdem Mert Babaoglu Irem Yilmaz Salih Karaismail Murat Mert Atmaca Mert Ilker Hayiroglu Tufan Cinar Ulas Bagci |
| author_facet | Vedat Cicek Sahhan Kilic Selami Dogan Almina Erdem Mert Babaoglu Irem Yilmaz Salih Karaismail Murat Mert Atmaca Mert Ilker Hayiroglu Tufan Cinar Ulas Bagci |
| author_sort | Vedat Cicek |
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| description | <i>Background and Objectives</i>: Studies have shown that inflammation markers can be used as prognostic tools in predicting acute ischemic stroke. In this study, we conducted a comparison of several inflammation scores in predicting left atrial thrombosis (LAT) in patients with ischemic stroke without AF. <i>Materials and Methods</i>: In this single-center, retrospective study, we included 303 consecutive patients with ischemic stroke. Each patient underwent a transesophageal echocardiography (TEE) examination within 10 days of admission to detect the presence of LAT. To identify independent predictors of LAT, we conducted a multivariate logistic regression analysis. <i>Results</i>: In total, 303 patients who had ischemic stroke were included in the analysis. LAT was detached in 34 patients at the time of the TEE examination. The patients were categorized into two groups based on their LAT status. The Prognostic Nutritional Index (PNI), HALP score, and C-reactive Protein–Albumin Ratio (CAR) were identified as statistically significant predictors of LAT. Based on the results of the multivariate regression analysis, the CAR emerged as the only independent predictor of LAT. <i>Conclusions</i>: Among several inflammation scores, the PNI, HALP, and CAR were statistically significant predictors of LAT in ischemic stroke patients without AF. CAR was identified as the optimal score for the prediction of LAT in patients with stroke and without AF. |
| format | Article |
| id | doaj-art-429fe94e625241bda45d29b03df941be |
| institution | Kabale University |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
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| series | Medicina |
| spelling | doaj-art-429fe94e625241bda45d29b03df941be2024-12-27T14:38:57ZengMDPI AGMedicina1010-660X1648-91442024-12-016012204610.3390/medicina60122046Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial FibrillationVedat Cicek0Sahhan Kilic1Selami Dogan2Almina Erdem3Mert Babaoglu4Irem Yilmaz5Salih Karaismail6Murat Mert Atmaca7Mert Ilker Hayiroglu8Tufan Cinar9Ulas Bagci10Machine & Hybrid Intelligence Lab, Department of Radiology, Northwestern University, 737 N. Michigan Avenue Suite 1600, Chicago, IL 60611, USADepartment of Cardiology, Sultan II. Abdulhamid Han Training and Research Hospital, Health Sciences University, 34668 Istanbul, TurkeyMalkara State Hospital, 59300 Tekirdag, TurkeyDepartment of Cardiology, Sultan II. Abdulhamid Han Training and Research Hospital, Health Sciences University, 34668 Istanbul, TurkeyDepartment of Cardiology, Sultan II. Abdulhamid Han Training and Research Hospital, Health Sciences University, 34668 Istanbul, TurkeyDepartment of Cardiology, Sultan II. Abdulhamid Han Training and Research Hospital, Health Sciences University, 34668 Istanbul, TurkeyDepartment of Neurology, Sultan II. Abdulhamid Han Training and Research Hospital, Health Sciences University, 34668 Istanbul, TurkeyDepartment of Neurology, Sultan II. Abdulhamid Han Training and Research Hospital, Health Sciences University, 34668 Istanbul, TurkeyDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, 34668 Istanbul, TurkeySchool of Medicine, University of Maryland, Baltimore, MD 21201, USAMachine & Hybrid Intelligence Lab, Department of Radiology, Northwestern University, 737 N. Michigan Avenue Suite 1600, Chicago, IL 60611, USA<i>Background and Objectives</i>: Studies have shown that inflammation markers can be used as prognostic tools in predicting acute ischemic stroke. In this study, we conducted a comparison of several inflammation scores in predicting left atrial thrombosis (LAT) in patients with ischemic stroke without AF. <i>Materials and Methods</i>: In this single-center, retrospective study, we included 303 consecutive patients with ischemic stroke. Each patient underwent a transesophageal echocardiography (TEE) examination within 10 days of admission to detect the presence of LAT. To identify independent predictors of LAT, we conducted a multivariate logistic regression analysis. <i>Results</i>: In total, 303 patients who had ischemic stroke were included in the analysis. LAT was detached in 34 patients at the time of the TEE examination. The patients were categorized into two groups based on their LAT status. The Prognostic Nutritional Index (PNI), HALP score, and C-reactive Protein–Albumin Ratio (CAR) were identified as statistically significant predictors of LAT. Based on the results of the multivariate regression analysis, the CAR emerged as the only independent predictor of LAT. <i>Conclusions</i>: Among several inflammation scores, the PNI, HALP, and CAR were statistically significant predictors of LAT in ischemic stroke patients without AF. CAR was identified as the optimal score for the prediction of LAT in patients with stroke and without AF.https://www.mdpi.com/1648-9144/60/12/2046thrombosisstrokeinflammation scoresleft atrial thrombosis |
| spellingShingle | Vedat Cicek Sahhan Kilic Selami Dogan Almina Erdem Mert Babaoglu Irem Yilmaz Salih Karaismail Murat Mert Atmaca Mert Ilker Hayiroglu Tufan Cinar Ulas Bagci Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation Medicina thrombosis stroke inflammation scores left atrial thrombosis |
| title | Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation |
| title_full | Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation |
| title_fullStr | Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation |
| title_full_unstemmed | Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation |
| title_short | Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation |
| title_sort | predictive value of inflammatory scores for left atrium thrombosis in ischemic stroke without atrial fibrillation |
| topic | thrombosis stroke inflammation scores left atrial thrombosis |
| url | https://www.mdpi.com/1648-9144/60/12/2046 |
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