Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn’s disease

Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn’s disease

IgA-coated fractions of the intestinal microbiota of Crohn’s disease (CD) patients have been shown to contain taxa that hallmark the compositional dysbiosis in CD microbiomes. However, the correlation between other cellular properties of intestinal bacteria and disease has not been explored further,...

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Main Authors: Lisa Budzinski, Gi-Ung Kang, René Riedel, Toni Sempert, Leonie Lietz, René Maier, Janine Büttner, Bettina Bochow, Marcell T. Tordai, Aayushi Shah, Amro Abbas, Tanisha Momtaz, Jannike L. Krause, Robin Kempkens, Katrin Lehman, Gitta A. Heinz, Anne E. Benken, Stefanie Bartsch, Kathleen Necke, Ute Hoffmann, Mir-Farzin Mashreghi, Robert Biesen, Tilmann Kallinich, Tobias Alexander, Bosse Jessen, Carl Weidinger, Britta Siegmund, Andreas Radbruch, Anja Schirbel, Benjamin Moser, Hyun-Dong Chang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Single-cell analysis
microbiota flow cytometry
microbiota phenotyping
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2452250
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