Impact of perfusion on neuronal development in human derived neuronal networks

Impact of perfusion on neuronal development in human derived neuronal networks

Advanced in vitro models of the brain have evolved in recent years from traditional two-dimensional (2D) ones, based on rodent derived cells, to three-dimensional (3D) ones, based on human neurons derived from induced pluripotent stem cells. To address the dynamic changes of the tissue microenvironm...

Full description

Saved in:

Bibliographic Details
Main Authors:	Donatella Di Lisa, Andrea Andolfi, Giacomo Masi, Giuseppe Uras, Pier Francesco Ferrari, Sergio Martinoia, Laura Pastorino
Format:	Article
Language:	English
Published:	AIP Publishing LLC 2024-12-01
Series:	APL Bioengineering
Online Access:	http://dx.doi.org/10.1063/5.0221911
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Chitosan suitability to adhesion, neuronal differentiation and maturation of hiPSCs compared to Matrigel coated substrates
by: Sara Grasselli, et al.
Published: (2025-03-01)

In vitro electrophysiological drug testing on neuronal networks derived from human induced pluripotent stem cells
by: Giulia Parodi, et al.
Published: (2024-11-01)

Human Motor Neuron Progenitor Transplantation Leads to Endogenous Neuronal Sparing in 3 Models of Motor Neuron Loss
by: Tanya J. Wyatt, et al.
Published: (2011-01-01)

Functional Properties of Human Stem Cell-Derived Neurons in Health and Disease
by: Jason P. Weick
Published: (2016-01-01)

Neuron-associated retroelement-derived protein Arc/Arg3.1 assists in the early stages of alphaherpesvirus infection in human neuronal cells.
by: Hiroko Kobayashi, et al.
Published: (2024-01-01)

Derivation and Identification of Motor Neurons from Human Urine-Derived Induced Pluripotent Stem Cells
by: Huan Yi, et al.
Published: (2018-01-01)

Hypothermia improves neuronal network recovery in a human-derived in vitro model of oxygen-deprivation.
by: Eva J H F Voogd, et al.
Published: (2024-01-01)

Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling
by: Ginetta Collo, et al.
Published: (2018-01-01)

Neuronal Electrical Activity in Neuronal Networks Induced by a Focused Femtosecond Laser
by: Yumi Segawa, et al.
Published: (2024-12-01)

The role of KNDy neurons in human reproductive health
by: Aki Oride, et al.
Published: (2024-08-01)

Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation
by: Hui Zhang, et al.
Published: (2025-03-01)

Toolbox Neurons
Published: (2018-08-01)

Integral Neuron: A New Concept for Nonlinear Neuron Modeling Using Weight Functions. Creation of XOR Neurons
by: Kostadin Yotov, et al.
Published: (2024-12-01)

A human single-neuron dataset for object recognition
by: Runnan Cao, et al.
Published: (2025-01-01)

Functional and Structural Investigation of Myenteric Neurons in the Human Colon
by: Kristin Elfers, et al.
Published: (2025-01-01)

Structural and functional alterations of neurons derived from sporadic Alzheimer’s disease hiPSCs are associated with downregulation of the LIMK1-cofilin axis
by: Raimondo Sollazzo, et al.
Published: (2024-12-01)

Spermidine Enhances Mitochondrial Bioenergetics in Young and Aged Human-Induced Pluripotent Stem Cell-Derived Neurons
by: Leonora Szabo, et al.
Published: (2024-12-01)

Protocol for single-molecule imaging of transcription and epigenetic factors in human neural stem cell-derived neurons
by: Yuri Atsumi, et al.
Published: (2024-12-01)

Evaluation of a biomarker for amyotrophic lateral sclerosis derived from a hypomethylated DNA signature of human motor neurons
by: Calum Harvey, et al.
Published: (2025-01-01)

Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far
by: T. J. Moore, et al.
Published: (2014-01-01)

Toolbox Modeling Neurons
Published: (2018-08-01)

Protocol to study neuronal membrane proteasome function in mouse peripheral sensory neurons
by: Emily R. Krueger, et al.
Published: (2025-03-01)

Purinergic Signaling Pathway in Human Olfactory Neuronal Precursor Cells
by: Héctor Solís-Chagoyán, et al.
Published: (2019-01-01)

Differential susceptibility of human motor neurons to infection with Usutu and West Nile virus
by: Eleanor M. Marshall, et al.
Published: (2024-09-01)

The Coexpression of Reelin and Neuronal Nitric Oxide Synthase in a Subpopulation of Dentate Gyrus Neurons Is Downregulated in Heterozygous Reeler Mice
by: Raquel Romay-Tallón, et al.
Published: (2010-01-01)

High-density multielectrode arrays bring cellular resolution to neuronal activity and network analyses of corticospinal motor neurons
by: Christopher A. Quintanilla, et al.
Published: (2025-01-01)

Glial cells improve Parkinson’s disease by modulating neuronal function and regulating neuronal ferroptosis
by: Mengzhu Li, et al.
Published: (2025-01-01)

Neuronal autosis: the self-destructive side of autophagy involved in hypoxic-ischemic neuronal death
by: Vanessa Ginet, et al.
Published: (2025-12-01)

Excitatory neuron-prone prion propagation and excitatory neuronal loss in prion-infected mice
by: Temuulen Erdenebat, et al.
Published: (2024-12-01)

Intrinsic and Extrinsic Neuronal Mechanisms in Temporal Coding: A Further Look at Neuronal Oscillations
by: Rémy Lestienne
Published: (1999-01-01)

The global neuronal workspace as a broadcasting network
by: Abel Wajnerman Paz
Published: (2022-11-01)

On the properties of input-to-output transformations in neuronal networks
by: Andrey Olypher, et al.
Published: (2015-12-01)

A Conformal Fractional Derivative-based Leaky Integrate-and-Fire Neuron Model
by: Reşat Mutlu, et al.
Published: (2022-06-01)

Neuron-derived neurotrophic factor promotes the differentiation of intramuscular and subcutaneous adipocytes in goat
by: An Li, et al.
Published: (2024-12-01)

Protocol for live imaging of axonal transport in iPSC-derived iNeurons
by: Dan Dou, et al.
Published: (2025-03-01)

Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation
by: María del Pilar Diego-Santiago, et al.
Published: (2025-02-01)

Identification of an early subset of cerebellar nuclei neurons in mice
by: Maryam Rahimi-Balaei, et al.
Published: (2024-12-01)

iPSC-derived human sensory neurons reveal a subset of TRPV1 antagonists as anti-pruritic compounds
by: Shermaine Huiping Tay, et al.
Published: (2024-12-01)

Axodendritic targeting of TAU and MAP2 and microtubule polarization in iPSC-derived versus SH-SY5Y-derived human neurons
by: Breuer Helen, et al.
Published: (2024-12-01)

LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies
by: Marc Emmenegger, et al.
Published: (2021-07-01)