Lung-Selective Delivery of mRNA-Encoding Anti-MERS-CoV Nanobody Exhibits Neutralizing Activity Both In Vitro and In Vivo

Lung-Selective Delivery of mRNA-Encoding Anti-MERS-CoV Nanobody Exhibits Neutralizing Activity Both In Vitro and In Vivo

<b>Background/Objectives</b>: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a highly pathogenic virus causing severe respiratory illness, with limited treatment options that are mostly supportive. The success of mRNA technology in COVID-19 vaccines has opened avenues for...

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Bibliographic Details
Main Authors: Yuhang Zhang, Chongyu Tian, Xinyang Yu, Guocan Yu, Xuelian Han, Yuan Wang, Haisheng Zhou, Shuai Zhang, Min Li, Tiantian Yang, Yali Sun, Wanbo Tai, Qi Yin, Guangyu Zhao
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Vaccines
Subjects:
mRNA
nanobody
lung-selective LNPs
MERS-CoV
Online Access:https://www.mdpi.com/2076-393X/12/12/1315
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https://www.mdpi.com/2076-393X/12/12/1315

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