Decreased Endothelin-1 bioavailability impairs aggressiveness of gallbladder cancer cells

Decreased Endothelin-1 bioavailability impairs aggressiveness of gallbladder cancer cells

Abstract Background Gallbladder cancer (GBC) is a highly lethal malignancy, often diagnosed at advanced stages when curative options are limited. Its rapid progression and high metastatic potential result in a 5-year survival rate below 5%. Recent evidence highlights the role of Endothelin-1 (ET1),...

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Main Authors: Jetzabel Vidal-Vidal, David Brown-Brown, Nelson Quilaqueo-Millaqueo, Gaspar Peña-Münzenmayer, Carlos Spichiger, Claudia Quezada-Monrás, Flavio Salazar-Onfray, Julio C. Tapia, Ignacio Niechi
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Biological Research
Online Access:https://doi.org/10.1186/s40659-025-00637-y
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https://doi.org/10.1186/s40659-025-00637-y

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