PATHOLOGICAL STUDIES ON NATURAL INFECTION OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND CO-INFECTION WITH PORCINE CIRCOVIRUS 2 ASSOCIATED POST-WEANING MULTI-SYSTEMIC WASTING SYNDROME AMONG SWINE HERDS OF KERALA, SOUTHERN INDIA
Porcine reproductive and respiratory syndrome virus (PRRSV) infection is an endemic, economically important disease affecting the swine industry worldwide. Since its first outbreak in 2013, this disease has been rapidly spreading to different parts of India. The objectives of this study were to sc...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
West Bengal Veterinary Alumni Association
2024-12-01
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| Series: | Exploratory Animal and Medical Research |
| Subjects: | |
| Online Access: | https://animalmedicalresearch.org/Vol.14_Issue-2_December_2024/PATHOLOGICAL%20STUDIES%20ON%20NATURAL%20INFECTION%20OF%20PORCINE%20REPRODUCTIVE.pdf |
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| Summary: | Porcine reproductive and respiratory syndrome virus (PRRSV) infection is an endemic,
economically important disease affecting the swine industry worldwide. Since its first outbreak in 2013, this
disease has been rapidly spreading to different parts of India. The objectives of this study were to screen
PRRSV among the swine population in Kerala, India, and to understand its pathological characteristics.
Pathological investigation revealed lesions in respiratory and lymphoid organs, and viral antigen distribution
was demonstrated using immunohistochemistry (IHC). Based on molecular screening using reverse
transcriptase polymerase chain reaction (RT-PCR) and immunohistochemistry (IHC), eight samples tested
positive for PRRSV. These results were corroborated by gross and histopathological findings. Post-weaning
multi-systemic wasting syndrome (PMWS) was also observed in two cases of PCV2-positive pigs co-infected
with PRRSV. Additionally, the findings confirmed the mutual association of PRRSV and PCV-2 in PMWS
among swine herds in southern India. The study identified the PRRSV strain as a Type II North American
genotype (PRRSV-2). Further investigation of strains that are currently circulating in India is crucial to
fully understand the diversity, distribution, and evolution of the virus.
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| ISSN: | 2277-470X 2319-247X |