A comprehensive review on natural macromolecular biopolymers for biomedical applications: Recent advancements, current challenges, and future outlooks
Versatile material properties coupled with high degree of biocompatibility and biodegradability has made biopolymers as potential candidates for diverse applications in the biomedical field. Natural biopolymers derived from various plant, animal and microbial sources with different biochemical compo...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Carbohydrate Polymer Technologies and Applications |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666893924001166 |
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| author | R Kalpana Manivannan Neha Sharma Vinay Kumar Iyyappan Jayaraj S. Vimal Mridul Umesh |
| author_facet | R Kalpana Manivannan Neha Sharma Vinay Kumar Iyyappan Jayaraj S. Vimal Mridul Umesh |
| author_sort | R Kalpana Manivannan |
| collection | DOAJ |
| description | Versatile material properties coupled with high degree of biocompatibility and biodegradability has made biopolymers as potential candidates for diverse applications in the biomedical field. Natural biopolymers derived from various plant, animal and microbial sources with different biochemical compositions are extensively used in biomaterial industry with or without further medication to their native form. Biopolymeric biomaterials have been employed in a wide range of biomedical applications like tissue engineering, drug delivery, bone regeneration, wound dressings and cardiovascular surgery. Carbohydrate based biopolymers and protein based biopolymers are extensively used for several applications in the biomedical field including cartilage regeneration, periodontal tissue regeneration, bone regeneration, corneal regeneration, drug delivery and wound healing. This review work presents a comprehensive outlook on the applications of various biopolymers in biomedical field. The work elaborates the biochemistry of these polymers with special focus on their crucial properties in the biomedical industry. Further a detailed description on the most recent application of various biopolymers in the biomedical filed is presented in this review. This work further summarizes the current challenges and future prospects in the use of biopolymers in biomedical field. |
| format | Article |
| id | doaj-art-422dc1ed1f084c4f9d30a2e3e6fdd0df |
| institution | Kabale University |
| issn | 2666-8939 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Carbohydrate Polymer Technologies and Applications |
| spelling | doaj-art-422dc1ed1f084c4f9d30a2e3e6fdd0df2024-12-13T11:06:18ZengElsevierCarbohydrate Polymer Technologies and Applications2666-89392024-12-018100536A comprehensive review on natural macromolecular biopolymers for biomedical applications: Recent advancements, current challenges, and future outlooksR Kalpana Manivannan0Neha Sharma1Vinay Kumar2Iyyappan Jayaraj3S. Vimal4Mridul Umesh5Institute of Biotechnology, Department of Bioengineering, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam 602105, IndiaDepartment of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam 602105, IndiaBiomaterials and Tissue Engineering (BITE) Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam 602105, India; Corresponding author.Department of Bioengineering, Institute of Biotechnology, Saveetha School of Engineering, SIMATS, Chennai 602105, IndiaDepartment of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam 602105, IndiaDepartment of Life Sciences, Christ University, Bengaluru 560029, Karnataka, IndiaVersatile material properties coupled with high degree of biocompatibility and biodegradability has made biopolymers as potential candidates for diverse applications in the biomedical field. Natural biopolymers derived from various plant, animal and microbial sources with different biochemical compositions are extensively used in biomaterial industry with or without further medication to their native form. Biopolymeric biomaterials have been employed in a wide range of biomedical applications like tissue engineering, drug delivery, bone regeneration, wound dressings and cardiovascular surgery. Carbohydrate based biopolymers and protein based biopolymers are extensively used for several applications in the biomedical field including cartilage regeneration, periodontal tissue regeneration, bone regeneration, corneal regeneration, drug delivery and wound healing. This review work presents a comprehensive outlook on the applications of various biopolymers in biomedical field. The work elaborates the biochemistry of these polymers with special focus on their crucial properties in the biomedical industry. Further a detailed description on the most recent application of various biopolymers in the biomedical filed is presented in this review. This work further summarizes the current challenges and future prospects in the use of biopolymers in biomedical field.http://www.sciencedirect.com/science/article/pii/S2666893924001166BiocompatibleNatural polymersTissue engineeringBiomedicineRegenerative medicine |
| spellingShingle | R Kalpana Manivannan Neha Sharma Vinay Kumar Iyyappan Jayaraj S. Vimal Mridul Umesh A comprehensive review on natural macromolecular biopolymers for biomedical applications: Recent advancements, current challenges, and future outlooks Carbohydrate Polymer Technologies and Applications Biocompatible Natural polymers Tissue engineering Biomedicine Regenerative medicine |
| title | A comprehensive review on natural macromolecular biopolymers for biomedical applications: Recent advancements, current challenges, and future outlooks |
| title_full | A comprehensive review on natural macromolecular biopolymers for biomedical applications: Recent advancements, current challenges, and future outlooks |
| title_fullStr | A comprehensive review on natural macromolecular biopolymers for biomedical applications: Recent advancements, current challenges, and future outlooks |
| title_full_unstemmed | A comprehensive review on natural macromolecular biopolymers for biomedical applications: Recent advancements, current challenges, and future outlooks |
| title_short | A comprehensive review on natural macromolecular biopolymers for biomedical applications: Recent advancements, current challenges, and future outlooks |
| title_sort | comprehensive review on natural macromolecular biopolymers for biomedical applications recent advancements current challenges and future outlooks |
| topic | Biocompatible Natural polymers Tissue engineering Biomedicine Regenerative medicine |
| url | http://www.sciencedirect.com/science/article/pii/S2666893924001166 |
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