Normal tissue complication probability model for severe radiation-induced lymphopenia in patients with pancreatic cancer treated with concurrent chemoradiotherapy

Normal tissue complication probability model for severe radiation-induced lymphopenia in patients with pancreatic cancer treated with concurrent chemoradiotherapy

Background and purpose: Radiation-induced lymphopenia (RIL) may be associated with a worse prognosis in pancreatic cancer. This study aimed to develop a normal tissue complication probability (NTCP) model to predict severe RIL in patients with pancreatic cancer undergoing concurrent chemoradiotherap...

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Main Authors: Fuki Koizumi, Norio Katoh, Takahiro Kanehira, Yasuyuki Kawamoto, Toru Nakamura, Tatsuhiko Kakisaka, Miyako Myojin, Noriaki Nishiyama, Akio Yonesaka, Manami Otsuka, Rikiya Takashina, Hideki Minatogawa, Hajime Higaki, Yusuke Uchinami, Hiroshi Taguchi, Kentaro Nishioka, Koichi Yasuda, Naoki Miyamoto, Isao Yokota, Keiji Kobashi, Hidefumi Aoyama
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Physics and Imaging in Radiation Oncology
Subjects:
Radiation-induced lymphopenia
Normal tissue complication probability model
Pancreatic cancer
Absolute lymphocyte count
Concurrent chemoradiotherapy
Kidney dose
Online Access:http://www.sciencedirect.com/science/article/pii/S240563162400160X
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http://www.sciencedirect.com/science/article/pii/S240563162400160X

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