Poricoic acid A attenuates renal fibrosis by inhibiting endoplasmic reticulum stress-mediated apoptosis

Poricoic acid A attenuates renal fibrosis by inhibiting endoplasmic reticulum stress-mediated apoptosis

Renal fibrosis is a common manifestation in the progression of chronic kidney disease (CKD) to kidney failure. Currently, there is no available therapy to prevent the progression of renal fibrosis. Poricoic acid A (PAA) isolated from Poria cocos shows notable antifibrotic effects. However, its poten...

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Bibliographic Details
Main Authors:	Hui Zhao, Tian Liu, Chang-E Yang, Yue-Huan Hu, Yan Niu, Sheng-Ping Lei, Lin Chen, Ming-Xia Zhang
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2024-11-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Fibrosis Poricoic acid A Endoplasmic reticulum stress Epithelial-to-mesenchymal transition Apoptosis
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100697&lng=en&tlng=en
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