Methods for assessing manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis

Background. Tracheal compression syndrome is one of the most severe complications of thyroid diseases and cicatricial tracheal stenosis, which is accompanied by respiratory failure. To assess the state of external respiratory function, standard research methods are used such as spirography, pneumota...

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Main Authors: V.V. Boyko, V.V. Kritsak, A.L. Sochnieva, V.V. Tkachenko
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2024-12-01
Series:Mìžnarodnij Endokrinologìčnij Žurnal
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Online Access:https://iej.zaslavsky.com.ua/index.php/journal/article/view/1466
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author V.V. Boyko
V.V. Kritsak
A.L. Sochnieva
V.V. Tkachenko
author_facet V.V. Boyko
V.V. Kritsak
A.L. Sochnieva
V.V. Tkachenko
author_sort V.V. Boyko
collection DOAJ
description Background. Tracheal compression syndrome is one of the most severe complications of thyroid diseases and cicatricial tracheal stenosis, which is accompanied by respiratory failure. To assess the state of external respiratory function, standard research methods are used such as spirography, pneumotachometry, and body plethysmography. Objective criteria for respiratory failure are indicators of changes in blood gas composition and acid-base balance. However, these methods can only be considered as auxi­liary in the diagnosis of tracheal stenosis. Methods for assessing the degree of respiratory failure in this severe pathology have not been studied sufficiently. The purpose is to study methods for assessing the manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis. Materials and methods. The study included 272 patients with laryngeal and tracheal compression stenosis caused by cicatricial tracheal stenosis: 105 with cicatricial tracheal stenosis and 167 with thyroid diseases. All participants were admitted to the clinic as emergencies and operated for urgent indications for tracheal compression syndrome at the V.T. Zaytsev Institute of General and Urgent Surgery of the NAMSU. The study was conducted in 2018–2024. Results. Laryngeal and tracheal stenosis primarily causes changes in the blood gas composition and acid-base balance of varying intensity. A decrease in blood О2 saturation, especially over an extended period, inevitably affects the functioning of organs with high energy consumption. This makes a comprehensive approach to the treatment of such patients obvious. Therapy should be aimed not only at restoring airway patency, but also at supporting the entire body. Conclusions. To increase the effectiveness of surgical and medical rehabilitation of patients with laryngeal and cervical tracheal stenosis, the outlined set of studies is necessary, which will allow substantiating the pathogenetic treatment of such patients.
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spelling doaj-art-41d8f93f0851464aa2732f48850d98df2025-01-12T12:20:34ZengZaslavsky O.Yu.Mìžnarodnij Endokrinologìčnij Žurnal2224-07212307-14272024-12-0120859359910.22141/2224-0721.20.8.2024.14661464Methods for assessing manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosisV.V. Boyko0https://orcid.org/0000-0002-3455-9705V.V. Kritsak1https://orcid.org/0000-0002-3712-6235A.L. Sochnieva2https://orcid.org/0000-0003-0106-5247V.V. Tkachenko3https://orcid.org/0009-0004-5194-4340Kharkiv National Medical University, Kharkiv, Ukraine; V.T. Zaytsev Institute of General and Urgent Surgery of the NAMSU, Kharkiv, UkraineV.T. Zaytsev Institute of General and Urgent Surgery of the NAMSU, Kharkiv, Ukraine; Medical Institute, National Technical University “Kharkiv Polytechnic Institute”, Kharkiv, UkraineMedical Institute, National Technical University “Kharkiv Polytechnic Institute”, Kharkiv, UkraineV.T. Zaytsev Institute of General and Urgent Surgery of the NAMSU, Kharkiv, Ukraine; Medical Institute, National Technical University “Kharkiv Polytechnic Institute”, Kharkiv, UkraineBackground. Tracheal compression syndrome is one of the most severe complications of thyroid diseases and cicatricial tracheal stenosis, which is accompanied by respiratory failure. To assess the state of external respiratory function, standard research methods are used such as spirography, pneumotachometry, and body plethysmography. Objective criteria for respiratory failure are indicators of changes in blood gas composition and acid-base balance. However, these methods can only be considered as auxi­liary in the diagnosis of tracheal stenosis. Methods for assessing the degree of respiratory failure in this severe pathology have not been studied sufficiently. The purpose is to study methods for assessing the manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis. Materials and methods. The study included 272 patients with laryngeal and tracheal compression stenosis caused by cicatricial tracheal stenosis: 105 with cicatricial tracheal stenosis and 167 with thyroid diseases. All participants were admitted to the clinic as emergencies and operated for urgent indications for tracheal compression syndrome at the V.T. Zaytsev Institute of General and Urgent Surgery of the NAMSU. The study was conducted in 2018–2024. Results. Laryngeal and tracheal stenosis primarily causes changes in the blood gas composition and acid-base balance of varying intensity. A decrease in blood О2 saturation, especially over an extended period, inevitably affects the functioning of organs with high energy consumption. This makes a comprehensive approach to the treatment of such patients obvious. Therapy should be aimed not only at restoring airway patency, but also at supporting the entire body. Conclusions. To increase the effectiveness of surgical and medical rehabilitation of patients with laryngeal and cervical tracheal stenosis, the outlined set of studies is necessary, which will allow substantiating the pathogenetic treatment of such patients.https://iej.zaslavsky.com.ua/index.php/journal/article/view/1466respiratory failurelaryngeal and tracheal compression syndromecicatricial tracheal stenosisthyroid disease
spellingShingle V.V. Boyko
V.V. Kritsak
A.L. Sochnieva
V.V. Tkachenko
Methods for assessing manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis
Mìžnarodnij Endokrinologìčnij Žurnal
respiratory failure
laryngeal and tracheal compression syndrome
cicatricial tracheal stenosis
thyroid disease
title Methods for assessing manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis
title_full Methods for assessing manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis
title_fullStr Methods for assessing manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis
title_full_unstemmed Methods for assessing manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis
title_short Methods for assessing manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis
title_sort methods for assessing manifestations of respiratory failure in patients with laryngeal and tracheal compression syndrome caused by thyroid diseases and cicatricial tracheal stenosis
topic respiratory failure
laryngeal and tracheal compression syndrome
cicatricial tracheal stenosis
thyroid disease
url https://iej.zaslavsky.com.ua/index.php/journal/article/view/1466
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AT alsochnieva methodsforassessingmanifestationsofrespiratoryfailureinpatientswithlaryngealandtrachealcompressionsyndromecausedbythyroiddiseasesandcicatricialtrachealstenosis
AT vvtkachenko methodsforassessingmanifestationsofrespiratoryfailureinpatientswithlaryngealandtrachealcompressionsyndromecausedbythyroiddiseasesandcicatricialtrachealstenosis