Urinary DNA-methylation and protein biomarkers identify urothelial carcinoma among other genitourinary diseases and cancer-free individuals

Urinary DNA-methylation and protein biomarkers identify urothelial carcinoma among other genitourinary diseases and cancer-free individuals

Abstract Background For more than 80 years, cystoscopy has been the gold standard for identification of urothelial carcinoma (UCa). Because of many factors, such as pain of the patients during this procedure or the costs involved, non-invasive detection of UCa remains a challenge. Herein, we verify...

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Bibliographic Details
Main Authors: Kerstin Lang, Christina U. Köhler, Katharina Wichert, Thomas Deix, Georg Bartsch, Gudrun Sommer, Christiane Lübke, Florian Roghmann, Moritz J. Reike, Harald Krentel, Katja Engellandt, Sven Schiermeier, Valentin Menke, Joachim Noldus, Thomas Behrens, Thomas Brüning, Heiko U. Käfferlein
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Bladder cancer
Verification
Urine
Biomarkers
DNA methylation
Online Access:https://doi.org/10.1186/s12967-024-05844-x
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