Construction of a Multi-Omics database for Paeonia lactiflora: A resource for comprehensive data integration and analysis
Abstract Background Paeonia lactiflora Pall. is a traditional medicinal plant widely used in East Asia, particularly for its roots, which are processed into various herbal remedies. With the advancement of omics technologies, significant genomic, transcriptomic, proteomic, and metabolomic data relat...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | BMC Plant Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12870-025-07032-5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849237601452556288 |
|---|---|
| author | Zongran Lu Ling Huang Somnuk Bunsupa Hamizah Shahirah Hamezah Xiaohui Tong Chuanshan Jin Jinmei Ou Rongchun Han |
| author_facet | Zongran Lu Ling Huang Somnuk Bunsupa Hamizah Shahirah Hamezah Xiaohui Tong Chuanshan Jin Jinmei Ou Rongchun Han |
| author_sort | Zongran Lu |
| collection | DOAJ |
| description | Abstract Background Paeonia lactiflora Pall. is a traditional medicinal plant widely used in East Asia, particularly for its roots, which are processed into various herbal remedies. With the advancement of omics technologies, significant genomic, transcriptomic, proteomic, and metabolomic data related to P. lactiflora have been generated. To facilitate the utilization of this wealth of information for research and applications, a multi-omics database specific to P. lactiflora was developed. Results This comprehensive multi-omics database includes genomic, transcriptomic, and proteomic datasets, as well as chemical compound profiles identified in various tissues and growth stages. The database also features data on key biosynthetic pathways, including those associated with monoterpenoid glycosides such as paeoniflorin, and provides tools for analyzing protein structures and interactions. Additionally, it summarizes P. lactiflora’s major active compounds, and highlights reported pharmacological effects. The database is organized into key functional modules: Home, Genome, Transcriptome, Proteome, Tools, Biosynthetic Pathways, Chemical Compounds, and Publications. Notably, the “Tools” module supports sequence alignment, pathway enrichment analysis (including Kyoto Encyclopedia of Genes and Genomes, KEGG), protein structure prediction, and primer design. Conclusions The multi-omics database (URL: http://210.22.121.250:8888/cosd/home/indexPage ) of P. lactiflora integrates extensive molecular and chemical data, providing a robust platform for researchers. It serves as a valuable resource for advancing studies on the cultivation, breeding, and molecular pharmacognosy of P. lactiflora and supports the development of its medicinal applications. |
| format | Article |
| id | doaj-art-41ababa97a7c40cda34c492d9d1b5321 |
| institution | Kabale University |
| issn | 1471-2229 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Plant Biology |
| spelling | doaj-art-41ababa97a7c40cda34c492d9d1b53212025-08-20T04:01:56ZengBMCBMC Plant Biology1471-22292025-08-0125111410.1186/s12870-025-07032-5Construction of a Multi-Omics database for Paeonia lactiflora: A resource for comprehensive data integration and analysisZongran Lu0Ling Huang1Somnuk Bunsupa2Hamizah Shahirah Hamezah3Xiaohui Tong4Chuanshan Jin5Jinmei Ou6Rongchun Han7School of pharmacy, Anhui University of Chinese MedicineSchool of pharmacy, Anhui University of Chinese MedicineFaculty of Pharmacy, Mahidol UniversityInstitute of Systems Biology, Universiti Kebangsaan MalaysiaSchool of Life Sciences, Anhui University of Chinese MedicineSchool of pharmacy, Anhui University of Chinese MedicineSchool of pharmacy, Anhui University of Chinese MedicineSchool of pharmacy, Anhui University of Chinese MedicineAbstract Background Paeonia lactiflora Pall. is a traditional medicinal plant widely used in East Asia, particularly for its roots, which are processed into various herbal remedies. With the advancement of omics technologies, significant genomic, transcriptomic, proteomic, and metabolomic data related to P. lactiflora have been generated. To facilitate the utilization of this wealth of information for research and applications, a multi-omics database specific to P. lactiflora was developed. Results This comprehensive multi-omics database includes genomic, transcriptomic, and proteomic datasets, as well as chemical compound profiles identified in various tissues and growth stages. The database also features data on key biosynthetic pathways, including those associated with monoterpenoid glycosides such as paeoniflorin, and provides tools for analyzing protein structures and interactions. Additionally, it summarizes P. lactiflora’s major active compounds, and highlights reported pharmacological effects. The database is organized into key functional modules: Home, Genome, Transcriptome, Proteome, Tools, Biosynthetic Pathways, Chemical Compounds, and Publications. Notably, the “Tools” module supports sequence alignment, pathway enrichment analysis (including Kyoto Encyclopedia of Genes and Genomes, KEGG), protein structure prediction, and primer design. Conclusions The multi-omics database (URL: http://210.22.121.250:8888/cosd/home/indexPage ) of P. lactiflora integrates extensive molecular and chemical data, providing a robust platform for researchers. It serves as a valuable resource for advancing studies on the cultivation, breeding, and molecular pharmacognosy of P. lactiflora and supports the development of its medicinal applications.https://doi.org/10.1186/s12870-025-07032-5Paeonia lactifloraDatabaseGenomeMulti-omicsData storage |
| spellingShingle | Zongran Lu Ling Huang Somnuk Bunsupa Hamizah Shahirah Hamezah Xiaohui Tong Chuanshan Jin Jinmei Ou Rongchun Han Construction of a Multi-Omics database for Paeonia lactiflora: A resource for comprehensive data integration and analysis BMC Plant Biology Paeonia lactiflora Database Genome Multi-omics Data storage |
| title | Construction of a Multi-Omics database for Paeonia lactiflora: A resource for comprehensive data integration and analysis |
| title_full | Construction of a Multi-Omics database for Paeonia lactiflora: A resource for comprehensive data integration and analysis |
| title_fullStr | Construction of a Multi-Omics database for Paeonia lactiflora: A resource for comprehensive data integration and analysis |
| title_full_unstemmed | Construction of a Multi-Omics database for Paeonia lactiflora: A resource for comprehensive data integration and analysis |
| title_short | Construction of a Multi-Omics database for Paeonia lactiflora: A resource for comprehensive data integration and analysis |
| title_sort | construction of a multi omics database for paeonia lactiflora a resource for comprehensive data integration and analysis |
| topic | Paeonia lactiflora Database Genome Multi-omics Data storage |
| url | https://doi.org/10.1186/s12870-025-07032-5 |
| work_keys_str_mv | AT zongranlu constructionofamultiomicsdatabaseforpaeonialactifloraaresourceforcomprehensivedataintegrationandanalysis AT linghuang constructionofamultiomicsdatabaseforpaeonialactifloraaresourceforcomprehensivedataintegrationandanalysis AT somnukbunsupa constructionofamultiomicsdatabaseforpaeonialactifloraaresourceforcomprehensivedataintegrationandanalysis AT hamizahshahirahhamezah constructionofamultiomicsdatabaseforpaeonialactifloraaresourceforcomprehensivedataintegrationandanalysis AT xiaohuitong constructionofamultiomicsdatabaseforpaeonialactifloraaresourceforcomprehensivedataintegrationandanalysis AT chuanshanjin constructionofamultiomicsdatabaseforpaeonialactifloraaresourceforcomprehensivedataintegrationandanalysis AT jinmeiou constructionofamultiomicsdatabaseforpaeonialactifloraaresourceforcomprehensivedataintegrationandanalysis AT rongchunhan constructionofamultiomicsdatabaseforpaeonialactifloraaresourceforcomprehensivedataintegrationandanalysis |