ECMO for bridging lung transplantation
Abstract Background With the shift in donor lung allocation from blood type and waiting order to the use of the lung allocation score (LAS) system, there are increasingly more cases of ECMO bridging lung transplantation. However, there are still some problems in case selection, implementation, and m...
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| Language: | English |
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BMC
2024-12-01
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| Series: | European Journal of Medical Research |
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| Online Access: | https://doi.org/10.1186/s40001-024-02239-y |
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| _version_ | 1846101327601467392 |
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| author | Chuhan Zhang Qingjing Wang Anwei Lu |
| author_facet | Chuhan Zhang Qingjing Wang Anwei Lu |
| author_sort | Chuhan Zhang |
| collection | DOAJ |
| description | Abstract Background With the shift in donor lung allocation from blood type and waiting order to the use of the lung allocation score (LAS) system, there are increasingly more cases of ECMO bridging lung transplantation. However, there are still some problems in case selection, implementation, and management. Methods We analyzed and summarized a series of data on ECMO bridging lung transplantation through an extensive literature review. Results The improvement of the lung transplant allocation system and the progress of ECMO technology have made the ECMO bridge to lung transplant more widely used in clinical practice. The selection of bridge patients is a crucial link in the success of transplantation, and accurate assessment of the patient before transplantation is necessary. The advantages and disadvantages of different bridge strategies exist, and the appropriate bridge strategy should be selected based on the patient's situation. Bleeding and thrombosis complications often occur during ECMO circulation, and there is currently no optimal anticoagulation strategy. The predictive score for bridge post-outcome is still subject to certain limitations. Conclusions ECMO bridging lung transplantation is suitable for patients waiting for lung transplantation when other respiratory support is ineffective or when hemodynamic instability occurs the disease is severe and the donor organ is easily obtainable. Patients aged 65 years or older, or have reversible multiple organ dysfunction should not be included as contraindications for ECMO bridging lung transplantation. |
| format | Article |
| id | doaj-art-4179b6fa44b44b768d948d51926c04d4 |
| institution | Kabale University |
| issn | 2047-783X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj-art-4179b6fa44b44b768d948d51926c04d42024-12-29T12:14:15ZengBMCEuropean Journal of Medical Research2047-783X2024-12-012911910.1186/s40001-024-02239-yECMO for bridging lung transplantationChuhan Zhang0Qingjing Wang1Anwei Lu2School of Medicine, Zhejiang Chinese Medical UniversityKey Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan International Medical College, Zhejiang Shuren UniversityDepartment of Critical Care Medicine, Shulan Hangzhou Hospital, Shulan International Medical College, Zhejiang Shuren UniversityAbstract Background With the shift in donor lung allocation from blood type and waiting order to the use of the lung allocation score (LAS) system, there are increasingly more cases of ECMO bridging lung transplantation. However, there are still some problems in case selection, implementation, and management. Methods We analyzed and summarized a series of data on ECMO bridging lung transplantation through an extensive literature review. Results The improvement of the lung transplant allocation system and the progress of ECMO technology have made the ECMO bridge to lung transplant more widely used in clinical practice. The selection of bridge patients is a crucial link in the success of transplantation, and accurate assessment of the patient before transplantation is necessary. The advantages and disadvantages of different bridge strategies exist, and the appropriate bridge strategy should be selected based on the patient's situation. Bleeding and thrombosis complications often occur during ECMO circulation, and there is currently no optimal anticoagulation strategy. The predictive score for bridge post-outcome is still subject to certain limitations. Conclusions ECMO bridging lung transplantation is suitable for patients waiting for lung transplantation when other respiratory support is ineffective or when hemodynamic instability occurs the disease is severe and the donor organ is easily obtainable. Patients aged 65 years or older, or have reversible multiple organ dysfunction should not be included as contraindications for ECMO bridging lung transplantation.https://doi.org/10.1186/s40001-024-02239-yLung transplantationECMOLung allocation scoreECMO bridging lung transplantation |
| spellingShingle | Chuhan Zhang Qingjing Wang Anwei Lu ECMO for bridging lung transplantation European Journal of Medical Research Lung transplantation ECMO Lung allocation score ECMO bridging lung transplantation |
| title | ECMO for bridging lung transplantation |
| title_full | ECMO for bridging lung transplantation |
| title_fullStr | ECMO for bridging lung transplantation |
| title_full_unstemmed | ECMO for bridging lung transplantation |
| title_short | ECMO for bridging lung transplantation |
| title_sort | ecmo for bridging lung transplantation |
| topic | Lung transplantation ECMO Lung allocation score ECMO bridging lung transplantation |
| url | https://doi.org/10.1186/s40001-024-02239-y |
| work_keys_str_mv | AT chuhanzhang ecmoforbridginglungtransplantation AT qingjingwang ecmoforbridginglungtransplantation AT anweilu ecmoforbridginglungtransplantation |