Formal [4 + 2] combined ionic and radical approach of vinylogous enaminonitriles to access highly substituted sulfonyl pyridazines

Formal [4 + 2] combined ionic and radical approach of vinylogous enaminonitriles to access highly substituted sulfonyl pyridazines

Abstract Pyridazine derivatives hold significant interest due to their broad applications in pharmaceuticals and materials science, where they serve as valuable scaffolds for bioactive compounds and functional materials. Here, we report a formal [4 + 2] reaction for the synthesis of 5’-sulfonyl-4’-a...

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Main Authors: Chanhyun Jung, Kwanghee Lee, Shanmugam Rajasekar, Ji-Youn Yim, Jaeuk Sim, Young Hee Lee, Jae-Hwan Kwak, Soonsil Hyun, Young Kee Kang, Mayavan Viji, Jae-Kyung Jung
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-024-01368-z
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