Hyaluronic acid–targeted topotecan liposomes improve therapeutic efficacy against lung cancer in animals

Hyaluronic acid–targeted topotecan liposomes improve therapeutic efficacy against lung cancer in animals

Lung cancer, as a serious threat to human health and life, necessitating urgent treatment and intervention. In this study, we prepared hyaluronic acid (HA)-targeted topotecan liposomes for site-specific delivery to tumor cells. The encapsulation efficiency, stability, chemical structure, and morphol...

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Bibliographic Details
Main Authors:	Gangqiang Xue, Lu Tang, Xinyan Pan, Sanni Li, Juan Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Series:	Frontiers in Oncology
Subjects:	hyaluronidase topotecan liposomes lung cancer pharmacokinetics
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1520274/full
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