Review on Exercise Regulation of Autophagy in Reducing Myocardial Ischemia Reperfusion Injury

Early recovery of myocardial perfusion after acute myocardial infarction is the most effective method to reduce the area of myocardial infarction and improve the clinical prognosis. However, hemodynamic reperfusion after myocardial ischemia may cause myocardial reperfusion injury.This study reviews...

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Main Authors: Xue WANG, Luwen ZHU, Hongyu LI, Yuhong CHEN, Qiang TANG
Format: Article
Language:English
Published: Editorial Office of Rehabilitation Medicine 2018-12-01
Series:康复学报
Subjects:
Online Access:http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2018.06067
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author Xue WANG
Luwen ZHU
Hongyu LI
Yuhong CHEN
Qiang TANG
author_facet Xue WANG
Luwen ZHU
Hongyu LI
Yuhong CHEN
Qiang TANG
author_sort Xue WANG
collection DOAJ
description Early recovery of myocardial perfusion after acute myocardial infarction is the most effective method to reduce the area of myocardial infarction and improve the clinical prognosis. However, hemodynamic reperfusion after myocardial ischemia may cause myocardial reperfusion injury.This study reviews the relationship between autophagy and related signaling pathways; autophagy which as a self-protective mechanism plays a dual role in the stage of myocardial ischemia and reperfusion;appropriate intensity of exercise training can regulate the level of autophagy of myocardial cells, so as to protect cardiac function and reduce myocardial ischemia-reperfusion injury.
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institution Kabale University
issn 2096-0328
language English
publishDate 2018-12-01
publisher Editorial Office of Rehabilitation Medicine
record_format Article
series 康复学报
spelling doaj-art-412cb1b023734cbca01be3f76493e5f92025-01-14T10:04:49ZengEditorial Office of Rehabilitation Medicine康复学报2096-03282018-12-0128677023128524Review on Exercise Regulation of Autophagy in Reducing Myocardial Ischemia Reperfusion InjuryXue WANGLuwen ZHUHongyu LIYuhong CHENQiang TANGEarly recovery of myocardial perfusion after acute myocardial infarction is the most effective method to reduce the area of myocardial infarction and improve the clinical prognosis. However, hemodynamic reperfusion after myocardial ischemia may cause myocardial reperfusion injury.This study reviews the relationship between autophagy and related signaling pathways; autophagy which as a self-protective mechanism plays a dual role in the stage of myocardial ischemia and reperfusion;appropriate intensity of exercise training can regulate the level of autophagy of myocardial cells, so as to protect cardiac function and reduce myocardial ischemia-reperfusion injury.http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2018.06067myocardial ischemia reperfusion injuryexerciseautophagyreview
spellingShingle Xue WANG
Luwen ZHU
Hongyu LI
Yuhong CHEN
Qiang TANG
Review on Exercise Regulation of Autophagy in Reducing Myocardial Ischemia Reperfusion Injury
康复学报
myocardial ischemia reperfusion injury
exercise
autophagy
review
title Review on Exercise Regulation of Autophagy in Reducing Myocardial Ischemia Reperfusion Injury
title_full Review on Exercise Regulation of Autophagy in Reducing Myocardial Ischemia Reperfusion Injury
title_fullStr Review on Exercise Regulation of Autophagy in Reducing Myocardial Ischemia Reperfusion Injury
title_full_unstemmed Review on Exercise Regulation of Autophagy in Reducing Myocardial Ischemia Reperfusion Injury
title_short Review on Exercise Regulation of Autophagy in Reducing Myocardial Ischemia Reperfusion Injury
title_sort review on exercise regulation of autophagy in reducing myocardial ischemia reperfusion injury
topic myocardial ischemia reperfusion injury
exercise
autophagy
review
url http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2018.06067
work_keys_str_mv AT xuewang reviewonexerciseregulationofautophagyinreducingmyocardialischemiareperfusioninjury
AT luwenzhu reviewonexerciseregulationofautophagyinreducingmyocardialischemiareperfusioninjury
AT hongyuli reviewonexerciseregulationofautophagyinreducingmyocardialischemiareperfusioninjury
AT yuhongchen reviewonexerciseregulationofautophagyinreducingmyocardialischemiareperfusioninjury
AT qiangtang reviewonexerciseregulationofautophagyinreducingmyocardialischemiareperfusioninjury