Comparative measurement of short-term fluoride release and inhibition of caries around restoration by ion releasing restorative materials: an in vitro study
Abstract The main objective of the current study is to compare short-term fluoride release of three ion releasing restorative materials and assess their inhibitory effect on secondary caries. Materials used in this study included, Self-adhesive hybrid composite (group A), Ion releasing flowable comp...
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Nature Portfolio
2025-01-01
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| author | Eman T. El-Adl Maha M. Ebaya El-Sayed E. Habib Nadia M. Zaghloul |
| author_facet | Eman T. El-Adl Maha M. Ebaya El-Sayed E. Habib Nadia M. Zaghloul |
| author_sort | Eman T. El-Adl |
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| description | Abstract The main objective of the current study is to compare short-term fluoride release of three ion releasing restorative materials and assess their inhibitory effect on secondary caries. Materials used in this study included, Self-adhesive hybrid composite (group A), Ion releasing flowable composite liner (group B), and alkasite restorative material (group C). Twenty-two discs were fabricated from each material for short-term fluoride release test, conducted on days 1, 7, and 14. For assessing secondary caries inhibition, sixty-six sound molar teeth were used and standardized class V cavities were prepared. Teeth were divided into three groups according to each material, followed by 800 cycles of thermocycling. Subsequently, teeth were immersed in a solution containing cariogenic bacteria for 30 days. After that, teeth were sectioned bucco-lingually and analyzed using a polarized light microscope to measure inhibition area, outer lesion depth, and extension. Data was statistically analyzed using different tests. The study results revealed a statistically significant differences in fluoride release existed among materials. Self-adhesive hybrid composite exhibited the highest fluoride release. Lesion extension and depth were statistically significantly greater next to Ion-releasing flowable composite liner. The inhibition areas next to the Self-adhesive hybrid composite were statistically significantly larger than the other two materials. In conclusion, all tested ion-releasing restorative materials displayed fluoride release and the potential to inhibit secondary caries formation. Self-adhesive hybrid composite demonstrated the highest fluoride-releasing potential and the greatest ability to inhibit secondary caries. Conversely, Ion-releasing flowable composite liner exhibited the least fluoride release with minimal secondary caries inhibition. Increasing fluoride release correlated with larger inhibition areas and reduced outer lesion depth and extension. |
| format | Article |
| id | doaj-art-411aadce5b20485cb6ecb869e783dc71 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-411aadce5b20485cb6ecb869e783dc712025-01-12T12:23:08ZengNature PortfolioScientific Reports2045-23222025-01-0115111010.1038/s41598-024-78918-xComparative measurement of short-term fluoride release and inhibition of caries around restoration by ion releasing restorative materials: an in vitro studyEman T. El-Adl0Maha M. Ebaya1El-Sayed E. Habib2Nadia M. Zaghloul3Conservative Dentistry Department, Faculty of Dentistry, Mansoura UniversityConservative Dentistry Department, Faculty of Dentistry, Mansoura UniversityMicrobiology and Immunology Department, Faculty of Pharmacy, Mansoura UniversityConservative Dentistry Department, Faculty of Dentistry, Mansoura UniversityAbstract The main objective of the current study is to compare short-term fluoride release of three ion releasing restorative materials and assess their inhibitory effect on secondary caries. Materials used in this study included, Self-adhesive hybrid composite (group A), Ion releasing flowable composite liner (group B), and alkasite restorative material (group C). Twenty-two discs were fabricated from each material for short-term fluoride release test, conducted on days 1, 7, and 14. For assessing secondary caries inhibition, sixty-six sound molar teeth were used and standardized class V cavities were prepared. Teeth were divided into three groups according to each material, followed by 800 cycles of thermocycling. Subsequently, teeth were immersed in a solution containing cariogenic bacteria for 30 days. After that, teeth were sectioned bucco-lingually and analyzed using a polarized light microscope to measure inhibition area, outer lesion depth, and extension. Data was statistically analyzed using different tests. The study results revealed a statistically significant differences in fluoride release existed among materials. Self-adhesive hybrid composite exhibited the highest fluoride release. Lesion extension and depth were statistically significantly greater next to Ion-releasing flowable composite liner. The inhibition areas next to the Self-adhesive hybrid composite were statistically significantly larger than the other two materials. In conclusion, all tested ion-releasing restorative materials displayed fluoride release and the potential to inhibit secondary caries formation. Self-adhesive hybrid composite demonstrated the highest fluoride-releasing potential and the greatest ability to inhibit secondary caries. Conversely, Ion-releasing flowable composite liner exhibited the least fluoride release with minimal secondary caries inhibition. Increasing fluoride release correlated with larger inhibition areas and reduced outer lesion depth and extension.https://doi.org/10.1038/s41598-024-78918-xFluoride releaseIon-releasing materialsCariogenic bacteriaSecondary caries |
| spellingShingle | Eman T. El-Adl Maha M. Ebaya El-Sayed E. Habib Nadia M. Zaghloul Comparative measurement of short-term fluoride release and inhibition of caries around restoration by ion releasing restorative materials: an in vitro study Scientific Reports Fluoride release Ion-releasing materials Cariogenic bacteria Secondary caries |
| title | Comparative measurement of short-term fluoride release and inhibition of caries around restoration by ion releasing restorative materials: an in vitro study |
| title_full | Comparative measurement of short-term fluoride release and inhibition of caries around restoration by ion releasing restorative materials: an in vitro study |
| title_fullStr | Comparative measurement of short-term fluoride release and inhibition of caries around restoration by ion releasing restorative materials: an in vitro study |
| title_full_unstemmed | Comparative measurement of short-term fluoride release and inhibition of caries around restoration by ion releasing restorative materials: an in vitro study |
| title_short | Comparative measurement of short-term fluoride release and inhibition of caries around restoration by ion releasing restorative materials: an in vitro study |
| title_sort | comparative measurement of short term fluoride release and inhibition of caries around restoration by ion releasing restorative materials an in vitro study |
| topic | Fluoride release Ion-releasing materials Cariogenic bacteria Secondary caries |
| url | https://doi.org/10.1038/s41598-024-78918-x |
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