Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited Setting

Conclusions: Upon the initiation of DTG, discernible elevations were observed in body weight, BMI and lipid levels. This study represents the first comprehensive assessment of lipid profiles and weight gain among this population in Zimbabwe, filling a critical gap in the existing literature. These f...

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Main Authors: Rudo Chakanetsa, Raylton P. Chikwati, Itai Chitungo, Cuthbert Musarurwa, Donald M. Tanyanyiwa, Justen Manasa, Vinie Kouamou
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:AIDS Research and Treatment
Online Access:http://dx.doi.org/10.1155/2024/4620951
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author Rudo Chakanetsa
Raylton P. Chikwati
Itai Chitungo
Cuthbert Musarurwa
Donald M. Tanyanyiwa
Justen Manasa
Vinie Kouamou
author_facet Rudo Chakanetsa
Raylton P. Chikwati
Itai Chitungo
Cuthbert Musarurwa
Donald M. Tanyanyiwa
Justen Manasa
Vinie Kouamou
author_sort Rudo Chakanetsa
collection DOAJ
description Conclusions: Upon the initiation of DTG, discernible elevations were observed in body weight, BMI and lipid levels. This study represents the first comprehensive assessment of lipid profiles and weight gain among this population in Zimbabwe, filling a critical gap in the existing literature. These findings, while indicative of short-term effects, underscore the imperative for further investigative efforts aimed at elucidating the prolonged consequences associated with DTG-induced weight gain and increased lipid levels and its underlying mechanisms.
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institution Kabale University
issn 2090-1259
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publishDate 2024-01-01
publisher Wiley
record_format Article
series AIDS Research and Treatment
spelling doaj-art-40d9f2a4c9894f0eb18b69b02b4c20b82024-11-22T00:00:04ZengWileyAIDS Research and Treatment2090-12592024-01-01202410.1155/2024/4620951Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited SettingRudo Chakanetsa0Raylton P. Chikwati1Itai Chitungo2Cuthbert Musarurwa3Donald M. Tanyanyiwa4Justen Manasa5Vinie Kouamou6Unit of Chemical PathologyDepartment of Chemical PathologyUnit of Chemical PathologyDepartment of Biomedical Laboratory SciencesUnit of Chemical PathologyDepartment of Internal MedicineDepartment of Internal MedicineConclusions: Upon the initiation of DTG, discernible elevations were observed in body weight, BMI and lipid levels. This study represents the first comprehensive assessment of lipid profiles and weight gain among this population in Zimbabwe, filling a critical gap in the existing literature. These findings, while indicative of short-term effects, underscore the imperative for further investigative efforts aimed at elucidating the prolonged consequences associated with DTG-induced weight gain and increased lipid levels and its underlying mechanisms.http://dx.doi.org/10.1155/2024/4620951
spellingShingle Rudo Chakanetsa
Raylton P. Chikwati
Itai Chitungo
Cuthbert Musarurwa
Donald M. Tanyanyiwa
Justen Manasa
Vinie Kouamou
Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited Setting
AIDS Research and Treatment
title Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited Setting
title_full Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited Setting
title_fullStr Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited Setting
title_full_unstemmed Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited Setting
title_short Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited Setting
title_sort weight and lipid levels in people living with hiv and initiating a dolutegravir based regimen in a resource limited setting
url http://dx.doi.org/10.1155/2024/4620951
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