Physicochemical and biological properties assessment of Pituranthos chloranthus from Algerian Sahara
Many plants are well-known for their use in traditional medicine to treat diseases associated with inflammations and oxidative stress. This study aimed to investigate a medicinal plant from the Saharan region of Algeria, Pituranthos chloranthus. Phytochemical analysis showed that it is rich in polyp...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | CyTA - Journal of Food |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/19476337.2024.2337001 |
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| author | Mekhadmi Nour Elhouda Mlik Randa Ben Amor Safia Boussebaa Walid Segueni Bentahar Assia Ramdani Messaoud Ghemam Amara Djilani Ayomide Victor Atoki Mohammed Messaoudi Adekunle Ismahil Adeniyi |
| author_facet | Mekhadmi Nour Elhouda Mlik Randa Ben Amor Safia Boussebaa Walid Segueni Bentahar Assia Ramdani Messaoud Ghemam Amara Djilani Ayomide Victor Atoki Mohammed Messaoudi Adekunle Ismahil Adeniyi |
| author_sort | Mekhadmi Nour Elhouda |
| collection | DOAJ |
| description | Many plants are well-known for their use in traditional medicine to treat diseases associated with inflammations and oxidative stress. This study aimed to investigate a medicinal plant from the Saharan region of Algeria, Pituranthos chloranthus. Phytochemical analysis showed that it is rich in polyphenols (8.93 ± 0.736 mg GAE/g) and flavonoids (0.78 ± 0.023 mg EQ/g). The treatment of hypoglycemic individuals with a P. chloranthus extract showed effectiveness when compared to control diabetic rats not treated with this extract. The latter showed a high average glucose at 3.11 ± 0.769 g/L when compared to the two treated rat groups, 0.8 ± 023 g/L and 0.54 ± 0.08 g/L when fed 500 and 250 mg/Kg body weight of P. chloranthus extract, respectively. The in vitro antioxidant evaluation, using the DPPH (IC50 = 0.156 ± 0.23 mg/mL) and FRAP (IC50 = 0.718 ± 0.09 mg/mL) tests and ratio to ascorbic acid 0.0037 ± 0.505 mg/mL showed an important antioxidant potential. |
| format | Article |
| id | doaj-art-40ace8ab85614ede893d50da67b3574b |
| institution | Kabale University |
| issn | 1947-6337 1947-6345 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | CyTA - Journal of Food |
| spelling | doaj-art-40ace8ab85614ede893d50da67b3574b2024-12-18T13:34:52ZengTaylor & Francis GroupCyTA - Journal of Food1947-63371947-63452024-12-0122110.1080/19476337.2024.2337001Physicochemical and biological properties assessment of Pituranthos chloranthus from Algerian SaharaMekhadmi Nour Elhouda0Mlik Randa1Ben Amor Safia2Boussebaa Walid3Segueni Bentahar Assia4Ramdani Messaoud5Ghemam Amara Djilani6Ayomide Victor Atoki7Mohammed Messaoudi8Adekunle Ismahil Adeniyi9Department of Biology, SNV Faculty, University of Chahid Hamma Lakhdar, El-Oued, AlgeriaNational Institute of Agronomic Research of Algeria, Adrar, AlgeriaLaboratory for Research on Medicinal and Aromatic Plants, Faculty of Nature Sciences and Life, University of Saad Dahlab, Blida, AlgeriaHigher School of Saharan Agronomy, El Oued, AlgeriaLaboratory of Phytotherapy Applied to Chronic Diseases SNV Faculty, University of Setif 1, Setif, AlgeriaLaboratory of Natural Resources Valorization, SNV Faculty, University of Setif 1, Setif, AlgeriaDepartment of Biology, SNV Faculty, University of Chahid Hamma Lakhdar, El-Oued, AlgeriaDepartment of Biochemistry, Kampala International University, Ishaka, UgandaNuclear Research Centre of Birine, Ain Oussera, AlgeriaDepartment of Physiology, Kampala International Universit, Ishaka, UgandaMany plants are well-known for their use in traditional medicine to treat diseases associated with inflammations and oxidative stress. This study aimed to investigate a medicinal plant from the Saharan region of Algeria, Pituranthos chloranthus. Phytochemical analysis showed that it is rich in polyphenols (8.93 ± 0.736 mg GAE/g) and flavonoids (0.78 ± 0.023 mg EQ/g). The treatment of hypoglycemic individuals with a P. chloranthus extract showed effectiveness when compared to control diabetic rats not treated with this extract. The latter showed a high average glucose at 3.11 ± 0.769 g/L when compared to the two treated rat groups, 0.8 ± 023 g/L and 0.54 ± 0.08 g/L when fed 500 and 250 mg/Kg body weight of P. chloranthus extract, respectively. The in vitro antioxidant evaluation, using the DPPH (IC50 = 0.156 ± 0.23 mg/mL) and FRAP (IC50 = 0.718 ± 0.09 mg/mL) tests and ratio to ascorbic acid 0.0037 ± 0.505 mg/mL showed an important antioxidant potential.https://www.tandfonline.com/doi/10.1080/19476337.2024.2337001P. chloranthusaqueous extractHPLCUPLC-ISI/MSantidiabeticantioxidant |
| spellingShingle | Mekhadmi Nour Elhouda Mlik Randa Ben Amor Safia Boussebaa Walid Segueni Bentahar Assia Ramdani Messaoud Ghemam Amara Djilani Ayomide Victor Atoki Mohammed Messaoudi Adekunle Ismahil Adeniyi Physicochemical and biological properties assessment of Pituranthos chloranthus from Algerian Sahara CyTA - Journal of Food P. chloranthus aqueous extract HPLC UPLC-ISI/MS antidiabetic antioxidant |
| title | Physicochemical and biological properties assessment of Pituranthos chloranthus from Algerian Sahara |
| title_full | Physicochemical and biological properties assessment of Pituranthos chloranthus from Algerian Sahara |
| title_fullStr | Physicochemical and biological properties assessment of Pituranthos chloranthus from Algerian Sahara |
| title_full_unstemmed | Physicochemical and biological properties assessment of Pituranthos chloranthus from Algerian Sahara |
| title_short | Physicochemical and biological properties assessment of Pituranthos chloranthus from Algerian Sahara |
| title_sort | physicochemical and biological properties assessment of pituranthos chloranthus from algerian sahara |
| topic | P. chloranthus aqueous extract HPLC UPLC-ISI/MS antidiabetic antioxidant |
| url | https://www.tandfonline.com/doi/10.1080/19476337.2024.2337001 |
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