Effects of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation (超声介导下药透疗法治疗阿片类药物相关性便秘的临床研究)
Objective To investigate the effect of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation. Methods Totally 60 cancer patients with opioid-related constipation were randomly divided into the control group and observation group, with 30 cases in each group....
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Journal of International Translational Medicine Limited
2023-09-01
|
| Series: | 中西医结合护理 |
| Subjects: | |
| Online Access: | http://www.zxyjhhl.cn/thesisDetails#10.55111/j.issn2709-1961.202304006 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846092992976257024 |
|---|---|
| author | ZHU Liting (朱丽婷) LIN Youyan (林友燕) YU Xinyan (俞新燕) |
| author_facet | ZHU Liting (朱丽婷) LIN Youyan (林友燕) YU Xinyan (俞新燕) |
| author_sort | ZHU Liting (朱丽婷) |
| collection | DOAJ |
| description | Objective To investigate the effect of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation. Methods Totally 60 cancer patients with opioid-related constipation were randomly divided into the control group and observation group, with 30 cases in each group. All patients were treatment with lactulose oral liquid medication (15mg per time, 3 times in a day), and those in the observation group were given a-week-course of ultrasound-mediated transdermal drug delivery therapy (30 minutes per time, once a day). The treatment efficacy was measured and compared between two groups. Results The overall effective rate of the observation group was higher than that of the control group (76. 67% vs. 43. 33%, P＜0. 05). Conclusion The ultrasound-mediated drug delivery is effective in the treatment of opioid-related constipation. (目的 观察超声介导下药透疗法治疗阿片类药物相关性便秘的临床效果。方法 将60例服用阿片类药物所致便秘的癌症患者采用随机数字表法分为对照组和观察组, 每组30例。两组患者均按医嘱口服乳果糖口服液, 15 mg/次, 3 次/d; 观察组患者在对照组基础上采用超声介导下药透疗法, 1 次/d, 30 min/次, 1周为1个疗程。疗程结束后比较两组患者便秘缓解情况。结果 观察组总有效率76. 67%(23/30), 高于对照组的43. 33%(13/30), 差异有统计学意义(P<0. 05)。结论 超声介导下药透疗法对阿片类药物相关便秘有确切疗效。) |
| format | Article |
| id | doaj-art-40a951ce9fd541bc89b2d7cb33915cea |
| institution | Kabale University |
| issn | 2709-1961 |
| language | zho |
| publishDate | 2023-09-01 |
| publisher | Journal of International Translational Medicine Limited |
| record_format | Article |
| series | 中西医结合护理 |
| spelling | doaj-art-40a951ce9fd541bc89b2d7cb33915cea2025-01-02T19:41:41ZzhoJournal of International Translational Medicine Limited中西医结合护理2709-19612023-09-019916817110.55111/j.issn2709-1961.202304006T202304006Effects of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation (超声介导下药透疗法治疗阿片类药物相关性便秘的临床研究)ZHU Liting (朱丽婷)0LIN Youyan (林友燕)1YU Xinyan (俞新燕)2Department of Integrative Medicine, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, 310005 (中国科学院大学附属肿瘤医院 浙江省肿瘤医院 中国科学院肿瘤与基础医学研究所中西医结合科, 浙江 杭州, 310005)Department of Integrative Medicine, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, 310005 (中国科学院大学附属肿瘤医院 浙江省肿瘤医院 中国科学院肿瘤与基础医学研究所中西医结合科, 浙江 杭州, 310005)Department of Integrative Medicine, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, 310005 (中国科学院大学附属肿瘤医院 浙江省肿瘤医院 中国科学院肿瘤与基础医学研究所中西医结合科, 浙江 杭州, 310005)Objective To investigate the effect of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation. Methods Totally 60 cancer patients with opioid-related constipation were randomly divided into the control group and observation group, with 30 cases in each group. All patients were treatment with lactulose oral liquid medication (15mg per time, 3 times in a day), and those in the observation group were given a-week-course of ultrasound-mediated transdermal drug delivery therapy (30 minutes per time, once a day). The treatment efficacy was measured and compared between two groups. Results The overall effective rate of the observation group was higher than that of the control group (76. 67% vs. 43. 33%, P＜0. 05). Conclusion The ultrasound-mediated drug delivery is effective in the treatment of opioid-related constipation. (目的 观察超声介导下药透疗法治疗阿片类药物相关性便秘的临床效果。方法 将60例服用阿片类药物所致便秘的癌症患者采用随机数字表法分为对照组和观察组, 每组30例。两组患者均按医嘱口服乳果糖口服液, 15 mg/次, 3 次/d; 观察组患者在对照组基础上采用超声介导下药透疗法, 1 次/d, 30 min/次, 1周为1个疗程。疗程结束后比较两组患者便秘缓解情况。结果 观察组总有效率76. 67%(23/30), 高于对照组的43. 33%(13/30), 差异有统计学意义(P<0. 05)。结论 超声介导下药透疗法对阿片类药物相关便秘有确切疗效。)http://www.zxyjhhl.cn/thesisDetails#10.55111/j.issn2709-1961.202304006ultrasound-mediateddrug deliveryopioid drugconstipation超声介导药透疗法阿片类药物便秘 |
| spellingShingle | ZHU Liting (朱丽婷) LIN Youyan (林友燕) YU Xinyan (俞新燕) Effects of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation (超声介导下药透疗法治疗阿片类药物相关性便秘的临床研究) 中西医结合护理 ultrasound-mediated drug delivery opioid drug constipation 超声介导 药透疗法 阿片类药物 便秘 |
| title | Effects of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation (超声介导下药透疗法治疗阿片类药物相关性便秘的临床研究) |
| title_full | Effects of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation (超声介导下药透疗法治疗阿片类药物相关性便秘的临床研究) |
| title_fullStr | Effects of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation (超声介导下药透疗法治疗阿片类药物相关性便秘的临床研究) |
| title_full_unstemmed | Effects of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation (超声介导下药透疗法治疗阿片类药物相关性便秘的临床研究) |
| title_short | Effects of ultrasound-mediated transdermal drug delivery in the treatment of opioid-related constipation (超声介导下药透疗法治疗阿片类药物相关性便秘的临床研究) |
| title_sort | effects of ultrasound mediated transdermal drug delivery in the treatment of opioid related constipation 超声介导下药透疗法治疗阿片类药物相关性便秘的临床研究 |
| topic | ultrasound-mediated drug delivery opioid drug constipation 超声介导 药透疗法 阿片类药物 便秘 |
| url | http://www.zxyjhhl.cn/thesisDetails#10.55111/j.issn2709-1961.202304006 |
| work_keys_str_mv | AT zhulitingzhūlìtíng effectsofultrasoundmediatedtransdermaldrugdeliveryinthetreatmentofopioidrelatedconstipationchāoshēngjièdǎoxiàyàotòuliáofǎzhìliáoāpiànlèiyàowùxiāngguānxìngbiànmìdelínchuángyánjiū AT linyouyanlínyǒuyàn effectsofultrasoundmediatedtransdermaldrugdeliveryinthetreatmentofopioidrelatedconstipationchāoshēngjièdǎoxiàyàotòuliáofǎzhìliáoāpiànlèiyàowùxiāngguānxìngbiànmìdelínchuángyánjiū AT yuxinyanyúxīnyàn effectsofultrasoundmediatedtransdermaldrugdeliveryinthetreatmentofopioidrelatedconstipationchāoshēngjièdǎoxiàyàotòuliáofǎzhìliáoāpiànlèiyàowùxiāngguānxìngbiànmìdelínchuángyánjiū |