Our experience in the diagnosis and treatment of peripheral exudative hemorrhagic chorioretinopathy
Purpose: To present our experience in the examination and treatment of patients with peripheral exudative hemorrhagic chorioretinopathy (PEHCR). Material and Methods: We retrospectively reviewed the medical records of patients who were finally clinically diagnosed with PEHCR in the 2022-2023 peri...
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Ukrainian Society of Ophthalmologists
2024-10-01
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| Series: | Journal of Ophthalmology |
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| Online Access: | https://ua.ozhurnal.com/index.php/files/article/view/187 |
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| author | I. O. Nasinnyk G. V. Levytska M. M. Umanets |
| author_facet | I. O. Nasinnyk G. V. Levytska M. M. Umanets |
| author_sort | I. O. Nasinnyk |
| collection | DOAJ |
| description | Purpose: To present our experience in the examination and treatment of patients with peripheral exudative hemorrhagic chorioretinopathy (PEHCR).
Material and Methods: We retrospectively reviewed the medical records of patients who were finally clinically diagnosed with PEHCR in the 2022-2023 period. History was collected and patients underwent ophthalmological examination including visual acuity, slit-lamp biomicroscopy, color fundus photography, fluorescein angiography and ocular ultrasound. All patients were treated with intravitreal anti-vascular endothelial growth factor (VEGF) therapy. One patient underwent vitreoretinal surgery.
Results: PEHCR was diagnosed in 11 patients (13 eyes), including two patients diagnosed with bilateral lesions. Clinical signs identified included a dome-shaped hemorrhagic detachment of the peripheral retinal pigment epithelium (RPE) with massive exudations. One patient underwent vitreoretinal surgery for vitreoretinal hemorrhage. On B-scan ultrasonography, the PEHCR lesion commonly presented as a dome or plateau-shaped mass with hollow or solid acoustic quality. Ten patients were treated with intravitreal aflibercept.
Conclusion: PEHCR is a chronic disease commonly associated with AMD. Detachment of the peripheral RPE is a major clinical manifestation of the disease, and may be complicated by sub-RPE hemorrhage in early disease. Anti-VEGF therapy is a major method of treatment whereas vitreoretinal surgery is indicated in complications accompanied by massive intravitreal hemorrhage or macula-threatening subretinal hemorrhage. Further investigation is needed to elucidate the etiology and pathogenesis of this entity and demonstrate the efficacy and safety of the aforementioned treatment modalities for PEHCR. |
| format | Article |
| id | doaj-art-4097b7538c1e4b4a82941c39ea380212 |
| institution | Kabale University |
| issn | 2412-8740 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Ukrainian Society of Ophthalmologists |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-4097b7538c1e4b4a82941c39ea3802122024-11-13T12:27:47ZengUkrainian Society of OphthalmologistsJournal of Ophthalmology2412-87402024-10-015101410.31288/oftalmolzh202451014Our experience in the diagnosis and treatment of peripheral exudative hemorrhagic chorioretinopathyI. O. Nasinnyk0https://orcid.org/0000-0002-1717-5777G. V. Levytska1M. M. Umanets2SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"Purpose: To present our experience in the examination and treatment of patients with peripheral exudative hemorrhagic chorioretinopathy (PEHCR). Material and Methods: We retrospectively reviewed the medical records of patients who were finally clinically diagnosed with PEHCR in the 2022-2023 period. History was collected and patients underwent ophthalmological examination including visual acuity, slit-lamp biomicroscopy, color fundus photography, fluorescein angiography and ocular ultrasound. All patients were treated with intravitreal anti-vascular endothelial growth factor (VEGF) therapy. One patient underwent vitreoretinal surgery. Results: PEHCR was diagnosed in 11 patients (13 eyes), including two patients diagnosed with bilateral lesions. Clinical signs identified included a dome-shaped hemorrhagic detachment of the peripheral retinal pigment epithelium (RPE) with massive exudations. One patient underwent vitreoretinal surgery for vitreoretinal hemorrhage. On B-scan ultrasonography, the PEHCR lesion commonly presented as a dome or plateau-shaped mass with hollow or solid acoustic quality. Ten patients were treated with intravitreal aflibercept. Conclusion: PEHCR is a chronic disease commonly associated with AMD. Detachment of the peripheral RPE is a major clinical manifestation of the disease, and may be complicated by sub-RPE hemorrhage in early disease. Anti-VEGF therapy is a major method of treatment whereas vitreoretinal surgery is indicated in complications accompanied by massive intravitreal hemorrhage or macula-threatening subretinal hemorrhage. Further investigation is needed to elucidate the etiology and pathogenesis of this entity and demonstrate the efficacy and safety of the aforementioned treatment modalities for PEHCR.https://ua.ozhurnal.com/index.php/files/article/view/187peripheral exudative hemorrhagic chorioretinopathypolypoidal choroidal vasculopathyhemorrhagic detachment of the pigment epithelium |
| spellingShingle | I. O. Nasinnyk G. V. Levytska M. M. Umanets Our experience in the diagnosis and treatment of peripheral exudative hemorrhagic chorioretinopathy Journal of Ophthalmology peripheral exudative hemorrhagic chorioretinopathy polypoidal choroidal vasculopathy hemorrhagic detachment of the pigment epithelium |
| title | Our experience in the diagnosis and treatment of peripheral exudative hemorrhagic chorioretinopathy |
| title_full | Our experience in the diagnosis and treatment of peripheral exudative hemorrhagic chorioretinopathy |
| title_fullStr | Our experience in the diagnosis and treatment of peripheral exudative hemorrhagic chorioretinopathy |
| title_full_unstemmed | Our experience in the diagnosis and treatment of peripheral exudative hemorrhagic chorioretinopathy |
| title_short | Our experience in the diagnosis and treatment of peripheral exudative hemorrhagic chorioretinopathy |
| title_sort | our experience in the diagnosis and treatment of peripheral exudative hemorrhagic chorioretinopathy |
| topic | peripheral exudative hemorrhagic chorioretinopathy polypoidal choroidal vasculopathy hemorrhagic detachment of the pigment epithelium |
| url | https://ua.ozhurnal.com/index.php/files/article/view/187 |
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