Microglial Lyzl4 Facilitates β‐Amyloid Clearance in Alzheimer's Disease

Microglial Lyzl4 Facilitates β‐Amyloid Clearance in Alzheimer's Disease

Abstract Alzheimer's Disease (AD) is a neurodegenerative condition characterized by the accumulation and deposition of amyloid‐β (Aβ) aggregates in the brain. Despite a wealth of research on the toxicity of Aβ and its role in synaptic damage, the mechanisms facilitating Aβ clearance are not yet...

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Bibliographic Details
Main Authors: Jie Pan, Jie Zhong, Ji Geng, Jane Oberhauser, Shihua Shi, Jun Wan
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
Alzheimer's disease (AD)
Lyzl4
microglia
phagocytosis
RNA‐seq
Online Access:https://doi.org/10.1002/advs.202412184
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