Low rank based FAZ segmentation in OCTA images

Abstract Optical Coherence Tomography Angiography (OCTA) is a non-invasive method for vascular imaging of different tissues. Several diseases can disturb the blood supplying of retinal tissues which leads to loss of blood vessels and a reduction in the vascular density of retinal tissue. This also c...

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Main Authors: Farnaz Sedighin, Fatemeh Rezaei, Maryam Monemian
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-07448-x
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author Farnaz Sedighin
Fatemeh Rezaei
Maryam Monemian
author_facet Farnaz Sedighin
Fatemeh Rezaei
Maryam Monemian
author_sort Farnaz Sedighin
collection DOAJ
description Abstract Optical Coherence Tomography Angiography (OCTA) is a non-invasive method for vascular imaging of different tissues. Several diseases can disturb the blood supplying of retinal tissues which leads to loss of blood vessels and a reduction in the vascular density of retinal tissue. This also changes the size and shape of the FAZ (Fovea Avascular Zone) in the retinal OCTA images. Considering this fact, FAZ segmentation and analyzing its shape, can be used for diagnosing of several eye-related diseases. This paper is devoted to propose new methods for accurate segmentation of FAZ from OCTA images. The proposed methods have three steps: first, FAZ localization, for which, two methods have been proposed. The first one used Low-rank Tensor Ring (TR) decomposition of OCTA images and the other one exploited morphological operators. In the second step, the de-noised OCTA image is used for FAZ segmentation exploiting the information of FAZ localization, and in the third step, the resulting segmented FAZ is refined to derive a clean area. To the best of our knowledge, this is the first time of using low-rank TR estimation for FAZ segmentation. Simulation results confirmed the performance of the proposed methods for an accurate FAZ segmentation.
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spelling doaj-art-408bca8a9949427a8f2d2d09a4e1b3a92025-08-20T03:42:41ZengNature PortfolioScientific Reports2045-23222025-07-0115111310.1038/s41598-025-07448-xLow rank based FAZ segmentation in OCTA imagesFarnaz Sedighin0Fatemeh Rezaei1Maryam Monemian2Medical Image and Signal Processing Research Center, School of Advanced Technologies in Medicine, Isfahan University of Medical SciencesMedical Image and Signal Processing Research Center, School of Advanced Technologies in Medicine, Isfahan University of Medical SciencesMedical Image and Signal Processing Research Center, School of Advanced Technologies in Medicine, Isfahan University of Medical SciencesAbstract Optical Coherence Tomography Angiography (OCTA) is a non-invasive method for vascular imaging of different tissues. Several diseases can disturb the blood supplying of retinal tissues which leads to loss of blood vessels and a reduction in the vascular density of retinal tissue. This also changes the size and shape of the FAZ (Fovea Avascular Zone) in the retinal OCTA images. Considering this fact, FAZ segmentation and analyzing its shape, can be used for diagnosing of several eye-related diseases. This paper is devoted to propose new methods for accurate segmentation of FAZ from OCTA images. The proposed methods have three steps: first, FAZ localization, for which, two methods have been proposed. The first one used Low-rank Tensor Ring (TR) decomposition of OCTA images and the other one exploited morphological operators. In the second step, the de-noised OCTA image is used for FAZ segmentation exploiting the information of FAZ localization, and in the third step, the resulting segmented FAZ is refined to derive a clean area. To the best of our knowledge, this is the first time of using low-rank TR estimation for FAZ segmentation. Simulation results confirmed the performance of the proposed methods for an accurate FAZ segmentation.https://doi.org/10.1038/s41598-025-07448-xOptical coherence tomography angiographyFAZ segmentationLow-rank estimationTensor ring decomposition
spellingShingle Farnaz Sedighin
Fatemeh Rezaei
Maryam Monemian
Low rank based FAZ segmentation in OCTA images
Scientific Reports
Optical coherence tomography angiography
FAZ segmentation
Low-rank estimation
Tensor ring decomposition
title Low rank based FAZ segmentation in OCTA images
title_full Low rank based FAZ segmentation in OCTA images
title_fullStr Low rank based FAZ segmentation in OCTA images
title_full_unstemmed Low rank based FAZ segmentation in OCTA images
title_short Low rank based FAZ segmentation in OCTA images
title_sort low rank based faz segmentation in octa images
topic Optical coherence tomography angiography
FAZ segmentation
Low-rank estimation
Tensor ring decomposition
url https://doi.org/10.1038/s41598-025-07448-x
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AT fatemehrezaei lowrankbasedfazsegmentationinoctaimages
AT maryammonemian lowrankbasedfazsegmentationinoctaimages