The effects of hypocaloric, high-protein diets on cardiovascular risk factors and weight loss in obese adults: a systematic review

Background: This systematic review has been undertaken in order to assess the effects of hypocaloric, high-protein diets on weight loss and cardiovascular risk factors such as serum lipid levels in metabolically healthy obese adults. The primary outcomes measured include changes in pre- and post- d...

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Main Authors: Martin Lauran, Ali Moghadas Jafari, Kosar Mohamed Ali, Seyed Mostafa Hosseini
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2024-09-01
Series:Journal of Biostatistics and Epidemiology
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Online Access:https://jbe.tums.ac.ir/index.php/jbe/article/view/1481
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author Martin Lauran
Ali Moghadas Jafari
Kosar Mohamed Ali
Seyed Mostafa Hosseini
author_facet Martin Lauran
Ali Moghadas Jafari
Kosar Mohamed Ali
Seyed Mostafa Hosseini
author_sort Martin Lauran
collection DOAJ
description Background: This systematic review has been undertaken in order to assess the effects of hypocaloric, high-protein diets on weight loss and cardiovascular risk factors such as serum lipid levels in metabolically healthy obese adults. The primary outcomes measured include changes in pre- and post- diet mean BMI, LDL-C, HDL-C, TAG, and TC levels.  Method: Four databases including: Embase, MEDLINE (via PubMed), Cochrane and Web of Science were searched with no restrictions on language or publication period. Clinicaltrials.gov was also searched in order to identify unpublished or on-going studies. Results: Three of four studies included in this systematic review noted a significantly greater loss in pre- and post- diet mean BMI levels in the hypocaloric, high-protein diet group as compared to hypocaloric, non-high protein diets (control). Whilst pre- and post-diet mean LDL-C, HDL-C, TAG, and TC levels did not differ significantly among hypocaloric, high-protein and control diet groups. Conclusion: Hypocaloric, high-protein diets had an unclear effect on blood-lipid levels as compared to control. Weight loss however was significantly greater in the hypocaloric, high-protein group as compared to other hypocaloric, non-high-protein diet groups. 
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series Journal of Biostatistics and Epidemiology
spelling doaj-art-4040a80b766a44ae872f4763b5c38cb52025-01-06T08:40:30ZengTehran University of Medical SciencesJournal of Biostatistics and Epidemiology2383-41962383-420X2024-09-0110110.18502/jbe.v10i1.17151The effects of hypocaloric, high-protein diets on cardiovascular risk factors and weight loss in obese adults: a systematic reviewMartin Lauran0Ali Moghadas Jafari1Kosar Mohamed Ali2Seyed Mostafa Hosseini3GKT School of Medical Education, King’s College London, London, UKFarhikhtegan Hospital, Azad university of Medical Sciences, Tehran, IranCollege of Medicine, University of Sulaimani, Sulaimani, IraqTUMS Background: This systematic review has been undertaken in order to assess the effects of hypocaloric, high-protein diets on weight loss and cardiovascular risk factors such as serum lipid levels in metabolically healthy obese adults. The primary outcomes measured include changes in pre- and post- diet mean BMI, LDL-C, HDL-C, TAG, and TC levels.  Method: Four databases including: Embase, MEDLINE (via PubMed), Cochrane and Web of Science were searched with no restrictions on language or publication period. Clinicaltrials.gov was also searched in order to identify unpublished or on-going studies. Results: Three of four studies included in this systematic review noted a significantly greater loss in pre- and post- diet mean BMI levels in the hypocaloric, high-protein diet group as compared to hypocaloric, non-high protein diets (control). Whilst pre- and post-diet mean LDL-C, HDL-C, TAG, and TC levels did not differ significantly among hypocaloric, high-protein and control diet groups. Conclusion: Hypocaloric, high-protein diets had an unclear effect on blood-lipid levels as compared to control. Weight loss however was significantly greater in the hypocaloric, high-protein group as compared to other hypocaloric, non-high-protein diet groups.  https://jbe.tums.ac.ir/index.php/jbe/article/view/1481High protein intakeCardiovascular risk factorsWeight lossLow caloric dietsObese adultsSystematic review
spellingShingle Martin Lauran
Ali Moghadas Jafari
Kosar Mohamed Ali
Seyed Mostafa Hosseini
The effects of hypocaloric, high-protein diets on cardiovascular risk factors and weight loss in obese adults: a systematic review
Journal of Biostatistics and Epidemiology
High protein intake
Cardiovascular risk factors
Weight loss
Low caloric diets
Obese adults
Systematic review
title The effects of hypocaloric, high-protein diets on cardiovascular risk factors and weight loss in obese adults: a systematic review
title_full The effects of hypocaloric, high-protein diets on cardiovascular risk factors and weight loss in obese adults: a systematic review
title_fullStr The effects of hypocaloric, high-protein diets on cardiovascular risk factors and weight loss in obese adults: a systematic review
title_full_unstemmed The effects of hypocaloric, high-protein diets on cardiovascular risk factors and weight loss in obese adults: a systematic review
title_short The effects of hypocaloric, high-protein diets on cardiovascular risk factors and weight loss in obese adults: a systematic review
title_sort effects of hypocaloric high protein diets on cardiovascular risk factors and weight loss in obese adults a systematic review
topic High protein intake
Cardiovascular risk factors
Weight loss
Low caloric diets
Obese adults
Systematic review
url https://jbe.tums.ac.ir/index.php/jbe/article/view/1481
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