Nivolumab-induced synovitis is characterized by florid T cell infiltration and rapid resolution with synovial biopsy-guided therapy

Background Immune checkpoint inhibitors (ICIs) are associated with rheumatic and musculoskeletal immune-related adverse events (irAEs) in 5%–20% of patients. Currently, patients refractory to corticosteroids and conventional disease-modifying antirheumatic drugs (cDMARD) are treated with biological...

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Bibliographic Details
Main Authors: Susanna Proudman, Sonja Klebe, William Murray-Brown, Tom D Wilsdon, Helen Weedon, Shawgi Sukumaran, Jennifer G Walker, Malcolm D Smith, Mihir D Wechalekar
Format: Article
Language:English
Published: BMJ Publishing Group 2020-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000281.full
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