Fatigue, interoplastic and nociplastic distress in myalgic encephalomyelitis/chronic fatigue syndrome, Gulf War Illness, and chronic idiopathic fatigue

Fatigue, interoplastic and nociplastic distress in myalgic encephalomyelitis/chronic fatigue syndrome, Gulf War Illness, and chronic idiopathic fatigue

IntroductionMyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Gulf War Illness (GWI) have similar profiles of pain (nociception), visceral interoception, and tenderness (central sensitization) that may be due to dysfunction of midbrain and medulla descending antinociceptive and antiint...

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Bibliographic Details
Main Authors: Emily Chen, Tamera Rudder, Charles Nwankwere, James N. Baraniuk
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neuroscience
Subjects:
fatigue
postexertional malaise
interoception
tenderness
dolorimetry
pain
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1530652/full
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