The median effective dose of oxycodone for acute postoperative pain after thoracoscopic pulmonary surgery with intercostal nerve blockin in patients of different ages: a dose-finding study protocol

The median effective dose of oxycodone for acute postoperative pain after thoracoscopic pulmonary surgery with intercostal nerve blockin in patients of different ages: a dose-finding study protocol

Abstract Background Oxycodone is an effective drug for controlling acute postoperative pain (APP), especially visceral pain. However, the effective dose needed for controlling APP depends on the surgical method and the patient age. Therefore, through use of the Dixon up-and-down method, this study i...

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Bibliographic Details
Main Authors: Min Zhang, Yi Liu, Jing Cao, Mengjie Liu, Xiaojun Gao, Na Guo, Chuansong Wei, Ye Zhu, Yongtao Sun, Jianbo Wu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Anesthesiology
Subjects:
Oxycodone
Intercostal nerve block
Different ages
Thoracoscopic pulmonary surgery
Acute postoperative pain
Median effective dose
Online Access:https://doi.org/10.1186/s12871-025-03198-5
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