Chronic myeloid leukemia following nasopharyngeal carcinoma
We describe a case of 48 year old woman with chronic myeloid leukemia (CML) occurring 13 years after a nasopharyngeal carcinoma treated with chemotherapy and radiotherapy. Bone marrow cytogenetic study demonstrated the presence of the t(9.22) and the molecular biology study showed rearrangement b2a2...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2014-08-01
|
| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Subjects: | |
| Online Access: | https://mjhid.org/index.php/mjhid/article/view/1914 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846098475990646784 |
|---|---|
| author | olfa kassar |
| author_facet | olfa kassar |
| author_sort | olfa kassar |
| collection | DOAJ |
| description | We describe a case of 48 year old woman with chronic myeloid leukemia (CML) occurring 13 years after a nasopharyngeal carcinoma treated with chemotherapy and radiotherapy. Bone marrow cytogenetic study demonstrated the presence of the t(9.22) and the molecular biology study showed rearrangement b2a2. She was managed with tyrosine kinase inhibitor but she died in blastic crisis. This case supports the observation that CML can develop as an important late complication after chemo and radiotherapy. |
| format | Article |
| id | doaj-art-3f956ee2453e4d49b925cc1fce63a8b6 |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2014-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-3f956ee2453e4d49b925cc1fce63a8b62025-01-02T00:23:26ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011Chronic myeloid leukemia following nasopharyngeal carcinomaolfa kassar0HEDI CHAKER HOSPITALWe describe a case of 48 year old woman with chronic myeloid leukemia (CML) occurring 13 years after a nasopharyngeal carcinoma treated with chemotherapy and radiotherapy. Bone marrow cytogenetic study demonstrated the presence of the t(9.22) and the molecular biology study showed rearrangement b2a2. She was managed with tyrosine kinase inhibitor but she died in blastic crisis. This case supports the observation that CML can develop as an important late complication after chemo and radiotherapy.https://mjhid.org/index.php/mjhid/article/view/1914therapy-related leukemiachronic myeloid leukemianasopharyngeal cancer |
| spellingShingle | olfa kassar Chronic myeloid leukemia following nasopharyngeal carcinoma Mediterranean Journal of Hematology and Infectious Diseases therapy-related leukemia chronic myeloid leukemia nasopharyngeal cancer |
| title | Chronic myeloid leukemia following nasopharyngeal carcinoma |
| title_full | Chronic myeloid leukemia following nasopharyngeal carcinoma |
| title_fullStr | Chronic myeloid leukemia following nasopharyngeal carcinoma |
| title_full_unstemmed | Chronic myeloid leukemia following nasopharyngeal carcinoma |
| title_short | Chronic myeloid leukemia following nasopharyngeal carcinoma |
| title_sort | chronic myeloid leukemia following nasopharyngeal carcinoma |
| topic | therapy-related leukemia chronic myeloid leukemia nasopharyngeal cancer |
| url | https://mjhid.org/index.php/mjhid/article/view/1914 |
| work_keys_str_mv | AT olfakassar chronicmyeloidleukemiafollowingnasopharyngealcarcinoma |