Perturbomics: CRISPR–Cas screening-based functional genomics approach for drug target discovery

Abstract Despite more than two decades since the completion of the first draft of the Human Genome Project, a substantial proportion of human genes remain poorly characterized in terms of their functions. Functional genomics aims to elucidate the roles and interactions of genes and genetic elements,...

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Bibliographic Details
Main Authors: Byung-Sun Park, Mieun Lee, Jaeyeol Kim, Tackhoon Kim
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01487-0
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