Gut microbiota and intestinal FXR siganlling involved in the alleviation of mulberry (Morus alba L.) leaf ethanol extract on type 2 diabetes mellitus in db/db mice

Gut microbiota and intestinal FXR siganlling involved in the alleviation of mulberry (Morus alba L.) leaf ethanol extract on type 2 diabetes mellitus in db/db mice

The potential mechanism of mulberry leaf against type 2 diabetes mellitus (T2DM) is not fully elucidated. Here, we hypothesized that the anti-T2DM of mulberry leaf ethanol extract (MLEE) is related to improvement of gut microbiota and bile acids (BAs) metabolism. Our results showed that MLEE alone c...

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Bibliographic Details
Main Authors: Ding-xiang Li, Sheng-qiu Xu, Han Jiang, Ya-Ting Li, Yan-lin Zhao, Peng Jin, Shuai Ji, Yan Du, Dao-Quan Tang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Functional Foods
Subjects:
Mulberry leaf ethanol extract
Type 2 diabetes mellitus
Gut microbiota
Bile acids
Farnesoid X receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624006030
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