Pattern of Medication Adherence, Spirituality and Viral Load amongst Adult Patients on Highly Active Antiretroviral Therapy in Rural Southwest Nigeria
Introduction: Previous studies have been conducted on medication adherence in Southwest Nigeria, but none of these has reported the relationship between highly active antiretroviral therapy (HAART) adherence, spirituality and viral load (VL) amongst people living with Human immunodeficiency virus (H...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Nigerian Postgraduate Medical Journal |
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| Online Access: | https://journals.lww.com/10.4103/npmj.npmj_176_24 |
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| author | Moronkeji Temitope Olanrewaju Olatutu Ololade Olanrewaju Azeez Oyemomi Ibrahim Tope Michael Ipinnimo Paul Oladapo Ajayi Oluwafunmilayo Kehinde Sito |
| author_facet | Moronkeji Temitope Olanrewaju Olatutu Ololade Olanrewaju Azeez Oyemomi Ibrahim Tope Michael Ipinnimo Paul Oladapo Ajayi Oluwafunmilayo Kehinde Sito |
| author_sort | Moronkeji Temitope Olanrewaju |
| collection | DOAJ |
| description | Introduction:
Previous studies have been conducted on medication adherence in Southwest Nigeria, but none of these has reported the relationship between highly active antiretroviral therapy (HAART) adherence, spirituality and viral load (VL) amongst people living with Human immunodeficiency virus (HIV)/AIDS, especially in rural settings of Southwestern Nigeria. This study assessed the pattern of medication adherence, spirituality and VL and ascertained the association of socio-demographics and spirituality on medication adherence amongst patients on HAART in rural Southwestern Nigeria.
Materials and Methods:
A hospital-based cross-sectional study involving 321 consented patients on HAART who were recruited by systematic sampling technique at the adult HIV clinic. Data were collected using an interviewer-administered questionnaire that assessed participants’ socio-demographic profiles, medication adherence and spirituality. Their blood samples were collected and their VLs were determined. The data were analysed using SPSS version 20. Logistic regression was done to identify the independent predictors of medication adherence.
Results:
The majority of the respondents reported a medium level of medication adherence (66.4%), a high level of spirituality (68.8%) and a low level of VL (67.3%). Amongst variables that had a statistically significant association with medication adherence were being educated, married, divorced, separated or widowed (P < 0.05). Furthermore, persons with high spirituality were 2.6 times more likely to be adherent to antiretroviral drugs when compared to persons with low spirituality (P < 0.05).
Conclusion:
It was shown that high spirituality is a positive predictor of medication adherence amongst patients on HAART. It, therefore, suggests that efforts deployed to improve the spirituality of these patients would most likely improve their medication adherence. |
| format | Article |
| id | doaj-art-3f492e1f67994c1a8de1ee5e9eb56e8a |
| institution | Kabale University |
| issn | 1117-1936 2468-6875 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Nigerian Postgraduate Medical Journal |
| spelling | doaj-art-3f492e1f67994c1a8de1ee5e9eb56e8a2025-01-07T09:47:56ZengWolters Kluwer Medknow PublicationsNigerian Postgraduate Medical Journal1117-19362468-68752024-12-0131429029810.4103/npmj.npmj_176_24Pattern of Medication Adherence, Spirituality and Viral Load amongst Adult Patients on Highly Active Antiretroviral Therapy in Rural Southwest NigeriaMoronkeji Temitope OlanrewajuOlatutu Ololade OlanrewajuAzeez Oyemomi IbrahimTope Michael IpinnimoPaul Oladapo AjayiOluwafunmilayo Kehinde SitoIntroduction: Previous studies have been conducted on medication adherence in Southwest Nigeria, but none of these has reported the relationship between highly active antiretroviral therapy (HAART) adherence, spirituality and viral load (VL) amongst people living with Human immunodeficiency virus (HIV)/AIDS, especially in rural settings of Southwestern Nigeria. This study assessed the pattern of medication adherence, spirituality and VL and ascertained the association of socio-demographics and spirituality on medication adherence amongst patients on HAART in rural Southwestern Nigeria. Materials and Methods: A hospital-based cross-sectional study involving 321 consented patients on HAART who were recruited by systematic sampling technique at the adult HIV clinic. Data were collected using an interviewer-administered questionnaire that assessed participants’ socio-demographic profiles, medication adherence and spirituality. Their blood samples were collected and their VLs were determined. The data were analysed using SPSS version 20. Logistic regression was done to identify the independent predictors of medication adherence. Results: The majority of the respondents reported a medium level of medication adherence (66.4%), a high level of spirituality (68.8%) and a low level of VL (67.3%). Amongst variables that had a statistically significant association with medication adherence were being educated, married, divorced, separated or widowed (P < 0.05). Furthermore, persons with high spirituality were 2.6 times more likely to be adherent to antiretroviral drugs when compared to persons with low spirituality (P < 0.05). Conclusion: It was shown that high spirituality is a positive predictor of medication adherence amongst patients on HAART. It, therefore, suggests that efforts deployed to improve the spirituality of these patients would most likely improve their medication adherence.https://journals.lww.com/10.4103/npmj.npmj_176_24human immunodeficiency virus/acquired immunodeficiency syndromemedication adherencerural nigeriaspiritualityviral load |
| spellingShingle | Moronkeji Temitope Olanrewaju Olatutu Ololade Olanrewaju Azeez Oyemomi Ibrahim Tope Michael Ipinnimo Paul Oladapo Ajayi Oluwafunmilayo Kehinde Sito Pattern of Medication Adherence, Spirituality and Viral Load amongst Adult Patients on Highly Active Antiretroviral Therapy in Rural Southwest Nigeria Nigerian Postgraduate Medical Journal human immunodeficiency virus/acquired immunodeficiency syndrome medication adherence rural nigeria spirituality viral load |
| title | Pattern of Medication Adherence, Spirituality and Viral Load amongst Adult Patients on Highly Active Antiretroviral Therapy in Rural Southwest Nigeria |
| title_full | Pattern of Medication Adherence, Spirituality and Viral Load amongst Adult Patients on Highly Active Antiretroviral Therapy in Rural Southwest Nigeria |
| title_fullStr | Pattern of Medication Adherence, Spirituality and Viral Load amongst Adult Patients on Highly Active Antiretroviral Therapy in Rural Southwest Nigeria |
| title_full_unstemmed | Pattern of Medication Adherence, Spirituality and Viral Load amongst Adult Patients on Highly Active Antiretroviral Therapy in Rural Southwest Nigeria |
| title_short | Pattern of Medication Adherence, Spirituality and Viral Load amongst Adult Patients on Highly Active Antiretroviral Therapy in Rural Southwest Nigeria |
| title_sort | pattern of medication adherence spirituality and viral load amongst adult patients on highly active antiretroviral therapy in rural southwest nigeria |
| topic | human immunodeficiency virus/acquired immunodeficiency syndrome medication adherence rural nigeria spirituality viral load |
| url | https://journals.lww.com/10.4103/npmj.npmj_176_24 |
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