Green RP-HPLC method for simultaneous quantification of epigallocatechin-3-gallate and rosmarinic acid in lipid-based nanocarriers and biological fluids: Quality by design-driven optimization and lean six sigma approach

Green RP-HPLC method for simultaneous quantification of epigallocatechin-3-gallate and rosmarinic acid in lipid-based nanocarriers and biological fluids: Quality by design-driven optimization and lean six sigma approach

This study presents the development and validation of a reverse-phase high-performance liquid chromatography (RP-HPLC) method for concurrent quantification of EGCG and RA in prepared lipid-based nanocarriers and biological fluids using a QbD approach, greenness assessment, and Six-Sigma methodology....

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Bibliographic Details
Main Authors: Rahul Koli, V.S. Mannur
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Green Analytical Chemistry
Subjects:
Epigallocatechin-3-gallate
Greenness assessment
Lean six-sigma method
Quality by design
Rosmarinic acid
RP-HPLC
Online Access:http://www.sciencedirect.com/science/article/pii/S2772577424000624
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