Lenalidomide-Associated ITP

Lenalidomide is a potent immunomodulatory agent being used increasingly for treatment of hematologic malignancies including multiple myeloma and myelodysplasia. The common toxicities of lenalidomide, including dose-limiting myelosuppression, are well described. However, the immunomodulatory properti...

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Bibliographic Details
Main Authors: Christina I. Herold, Cristina Gasparetto, Gowthami M. Arepally
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2011/638020
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Summary:Lenalidomide is a potent immunomodulatory agent being used increasingly for treatment of hematologic malignancies including multiple myeloma and myelodysplasia. The common toxicities of lenalidomide, including dose-limiting myelosuppression, are well described. However, the immunomodulatory properties of lenalidomide may give rise to unexpected autoimmune complications. Herein, we describe a case of immune thrombocytopenic purpura (ITP) associated with use of lenalidomide.
ISSN:2090-6560
2090-6579