Allogeneic CD4 T Cells Sustain Effective BK Polyomavirus-Specific CD8 T Cell Response in Kidney Transplant Recipients

Allogeneic CD4 T Cells Sustain Effective BK Polyomavirus-Specific CD8 T Cell Response in Kidney Transplant Recipients

Introduction: BK polyomavirus-associated nephropathy (BKPyVAN) is a significant complication in kidney transplant recipients (KTRs), associated with a higher level of plasmatic BK polyomavirus (BKPyV) replication and leading to poor graft survival. Methods: We prospectively followed-up with 100 KTRs...

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Main Authors: Manon Dekeyser, Marie-Ghislaine de Goër de Herve, Houria Hendel-Chavez, Romain Lhotte, Ivan Scriabine, Karen Bargiel, Emmanuelle Boutin, Florence Herr, Jean-Luc Taupin, Yassine Taoufik, Antoine Durrbach
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Kidney International Reports
Subjects:
BK polyomavirus reactivation
BK polyomavirus-associated nephropathy
BK polyomavirus-specific T cell
donor-recipient HLA divergence
kidney transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S246802492401708X
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