Secondary overactive bladder syndrome with restless legs syndrome following cerebral infarction: report of 2 cases

Secondary overactive bladder syndrome with restless legs syndrome following cerebral infarction: report of 2 cases

Abstract Background Previous research has commonly regarded overactive bladder syndrome (OAB) and restless legs syndrome (RLS) as distinct disorders in terms of their underlying causes, clinical diagnosis, and treatment approaches. However, there is evidence of an overlap in the occurrence of these...

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Bibliographic Details
Main Authors: Ying Cui, Qiang Huang, Yitong Du, Lin Wang, Shiya Wang, Wenlu Zhao, Houzhen Tuo
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Geriatrics
Subjects:
Overactive bladder syndrome
Restless legs syndrome
Restless bladder syndrome
Cerebral infarction
Dopaminergic agonists
Online Access:https://doi.org/10.1186/s12877-025-05724-z
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Summary:Abstract Background Previous research has commonly regarded overactive bladder syndrome (OAB) and restless legs syndrome (RLS) as distinct disorders in terms of their underlying causes, clinical diagnosis, and treatment approaches. However, there is evidence of an overlap in the occurrence of these two conditions following cerebral infarction(CI). Specifically, restless bladder syndrome (RBS), a subtype of RLS, exhibits symptoms similar to those of OAB. Consequently, further investigation is warranted to better understand the relationship between these two disorders. Case presentation In this report, we present the cases of two patients who presented with both OAB following CI, along with RLS. Following administration of oral pramipexole, both nocturia and RLS exhibited prompt and efficient alleviation. Conclusions There may exist a shared pathological foundation between certain RLS cases and OAB. In instances where patients exhibit evident OAB symptoms following CI and concurrently experience RLS, it is advisable to prioritize the administration of dopaminergic agonists over M receptor inhibitors and β3 agonists. Furthermore, it is plausible that the RBS or a subset of RLS cases could potentially be classified as a form of OAB, although this correlation has yet to be definitively established.
ISSN:1471-2318

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