Prevalence and Associated Factors of Dengue Virus Circulation in the Rural Community, Handeni District in Tanga, Tanzania
Dengue virus is among the most important re-emerging arbovirus that causes global public health attention. Dengue has historically been thought of as an urban disease that frequently occurs in rapidly urbanized settings. However, dengue has become more widespread in rural regions in recent years. Un...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2023/5576300 |
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| author | Debora C. Kajeguka Francis M. Mponela Emmanuel Mkumbo Anna N. Kaaya Daniel Lasway Robert D. Kaaya Michael Alifrangis Emmanuel Elanga-Ndille Blandina T. Mmbaga Reginald Kavishe |
| author_facet | Debora C. Kajeguka Francis M. Mponela Emmanuel Mkumbo Anna N. Kaaya Daniel Lasway Robert D. Kaaya Michael Alifrangis Emmanuel Elanga-Ndille Blandina T. Mmbaga Reginald Kavishe |
| author_sort | Debora C. Kajeguka |
| collection | DOAJ |
| description | Dengue virus is among the most important re-emerging arbovirus that causes global public health attention. Dengue has historically been thought of as an urban disease that frequently occurs in rapidly urbanized settings. However, dengue has become more widespread in rural regions in recent years. Understanding the changing dengue epidemiology in different geographical settings is important for targeted intervention. In Tanzania, dengue fever is not frequently reported because of the poor surveillance infrastructure, underestimation, and a lack of consideration of dengue as a priority. Therefore, the true burden as well as the risk factors for increased transmission has not been fully ascertained, particularly in rural areas. A cross-sectional community-based study was conducted in June 2021, involving a total of 362 participants of all age groups. We investigated the prevalence of acute dengue infection, seroprevalence, and associated factors among the community in three villages of the rural Handeni district. The prevalence of acute dengue infection (based on PCR) was 2.2% (8/362). Dengue-specific IgM and IgG antibodies were detected in 3.3% (12/362) and 5.2% (19/362) of the participants, respectively. Adult participants who were having vegetation around their houses were more likely to be DENV seropositive (AOR = 2.4, CI = 1.88–4.18, p value = 0.05). Children living in houses with garbage pit around their households were less likely to be DENV seropositive (AOR = 0.13, CI = 0.03–0.56, p value <0.01). DENV continues to circulate in rural Tanzania, causes an alarming situation, and necessitates prompt public health action to enhance vector surveillance and control in rural communities. |
| format | Article |
| id | doaj-art-3e18f338e0064c43b2626458450f6f3c |
| institution | Kabale University |
| issn | 1687-9694 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-3e18f338e0064c43b2626458450f6f3c2025-08-20T03:55:41ZengWileyJournal of Tropical Medicine1687-96942023-01-01202310.1155/2023/5576300Prevalence and Associated Factors of Dengue Virus Circulation in the Rural Community, Handeni District in Tanga, TanzaniaDebora C. Kajeguka0Francis M. Mponela1Emmanuel Mkumbo2Anna N. Kaaya3Daniel Lasway4Robert D. Kaaya5Michael Alifrangis6Emmanuel Elanga-Ndille7Blandina T. Mmbaga8Reginald Kavishe9Kilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeCentre for Medical ParasitologyCentre for Research in Infectious Diseases (CRID)Kilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeDengue virus is among the most important re-emerging arbovirus that causes global public health attention. Dengue has historically been thought of as an urban disease that frequently occurs in rapidly urbanized settings. However, dengue has become more widespread in rural regions in recent years. Understanding the changing dengue epidemiology in different geographical settings is important for targeted intervention. In Tanzania, dengue fever is not frequently reported because of the poor surveillance infrastructure, underestimation, and a lack of consideration of dengue as a priority. Therefore, the true burden as well as the risk factors for increased transmission has not been fully ascertained, particularly in rural areas. A cross-sectional community-based study was conducted in June 2021, involving a total of 362 participants of all age groups. We investigated the prevalence of acute dengue infection, seroprevalence, and associated factors among the community in three villages of the rural Handeni district. The prevalence of acute dengue infection (based on PCR) was 2.2% (8/362). Dengue-specific IgM and IgG antibodies were detected in 3.3% (12/362) and 5.2% (19/362) of the participants, respectively. Adult participants who were having vegetation around their houses were more likely to be DENV seropositive (AOR = 2.4, CI = 1.88–4.18, p value = 0.05). Children living in houses with garbage pit around their households were less likely to be DENV seropositive (AOR = 0.13, CI = 0.03–0.56, p value <0.01). DENV continues to circulate in rural Tanzania, causes an alarming situation, and necessitates prompt public health action to enhance vector surveillance and control in rural communities.http://dx.doi.org/10.1155/2023/5576300 |
| spellingShingle | Debora C. Kajeguka Francis M. Mponela Emmanuel Mkumbo Anna N. Kaaya Daniel Lasway Robert D. Kaaya Michael Alifrangis Emmanuel Elanga-Ndille Blandina T. Mmbaga Reginald Kavishe Prevalence and Associated Factors of Dengue Virus Circulation in the Rural Community, Handeni District in Tanga, Tanzania Journal of Tropical Medicine |
| title | Prevalence and Associated Factors of Dengue Virus Circulation in the Rural Community, Handeni District in Tanga, Tanzania |
| title_full | Prevalence and Associated Factors of Dengue Virus Circulation in the Rural Community, Handeni District in Tanga, Tanzania |
| title_fullStr | Prevalence and Associated Factors of Dengue Virus Circulation in the Rural Community, Handeni District in Tanga, Tanzania |
| title_full_unstemmed | Prevalence and Associated Factors of Dengue Virus Circulation in the Rural Community, Handeni District in Tanga, Tanzania |
| title_short | Prevalence and Associated Factors of Dengue Virus Circulation in the Rural Community, Handeni District in Tanga, Tanzania |
| title_sort | prevalence and associated factors of dengue virus circulation in the rural community handeni district in tanga tanzania |
| url | http://dx.doi.org/10.1155/2023/5576300 |
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