Perfusion parameters and target values during extracorporeal cardiopulmonary resuscitation: a scoping review protocol

Introduction Extracorporeal cardiopulmonary resuscitation (eCPR) is increasingly applied in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) patients. Treatment results are promising, but the efficacy and safety of the procedure are still unclear. Currently, there are no r...

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Main Authors: Lars Saemann, Christine Schmucker, Lisa Rösner, Friedhelm Beyersdorf, Christoph Benk
Format: Article
Language:English
Published: BMJ Publishing Group 2019-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/8/e030562.full
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author Lars Saemann
Christine Schmucker
Lisa Rösner
Friedhelm Beyersdorf
Christoph Benk
author_facet Lars Saemann
Christine Schmucker
Lisa Rösner
Friedhelm Beyersdorf
Christoph Benk
author_sort Lars Saemann
collection DOAJ
description Introduction Extracorporeal cardiopulmonary resuscitation (eCPR) is increasingly applied in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) patients. Treatment results are promising, but the efficacy and safety of the procedure are still unclear. Currently, there are no recommended target perfusion parameters during eCPR, the lack of which could result in inadequate (re)perfusion. We aim to perform a scoping review to explore the current literature addressing target perfusion parameters, target values, corresponding survival rates and neurologic outcomes in OHCA and IHCA patients treated with eCPR.Methods and analysis To identify relevant research, we will conduct searches in the electronic databases MEDLINE, EMBASE, Social Science Citation Index, Social Science Citation Index Expanded and the Cochrane library. We will also check references of relevant articles and perform a cited reference research (forward citation tracking).Two independent reviewers will screen titles and abstracts, check full texts for eligibility and perform data extraction. We will resolve dissent by consensus, moderated by a third reviewer. We will include observational and controlled studies addressing target perfusion parameters and outcomes such as survival rates and neurologic findings in OHCA and IHCA patients treated with eCPR. Data extraction tables will be set up, including study and patients’ characteristics, aim of study, details on eCPR including target perfusion parameters and reported outcomes. We will summarise the data using tables and figures (ie, bubble plot) to present the research landscape and to describe potential clusters and/or gaps.Ethics and dissemination An ethical approval is not needed. We intend to publish the scoping review in a peer-reviewed journal and present results on a scientific meeting.
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spelling doaj-art-3dfaf94b4c784b38b57d58c5f3c2047b2024-11-25T21:30:11ZengBMJ Publishing GroupBMJ Open2044-60552019-08-019810.1136/bmjopen-2019-030562Perfusion parameters and target values during extracorporeal cardiopulmonary resuscitation: a scoping review protocolLars Saemann0Christine Schmucker1Lisa Rösner2Friedhelm Beyersdorf3Christoph Benk41 Department of Cardiovascular Surgery, University Hospital Freiburg Cardiac Centre Freiburg Bad Krozingen Freiburg Branch, Freiburg, GermanyInstitute for Evidence in Medicine (for Cochrane Germany Foundation), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Baden-Württemberg, Germany1 Department of Cardiovascular Surgery, University Hospital Freiburg Cardiac Centre Freiburg Bad Krozingen Freiburg Branch, Freiburg, Germany14 Department of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Hospital Freiburg, Freiburg, Germany1 Department of Cardiovascular Surgery, University Hospital Freiburg Cardiac Centre Freiburg Bad Krozingen Freiburg Branch, Freiburg, GermanyIntroduction Extracorporeal cardiopulmonary resuscitation (eCPR) is increasingly applied in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) patients. Treatment results are promising, but the efficacy and safety of the procedure are still unclear. Currently, there are no recommended target perfusion parameters during eCPR, the lack of which could result in inadequate (re)perfusion. We aim to perform a scoping review to explore the current literature addressing target perfusion parameters, target values, corresponding survival rates and neurologic outcomes in OHCA and IHCA patients treated with eCPR.Methods and analysis To identify relevant research, we will conduct searches in the electronic databases MEDLINE, EMBASE, Social Science Citation Index, Social Science Citation Index Expanded and the Cochrane library. We will also check references of relevant articles and perform a cited reference research (forward citation tracking).Two independent reviewers will screen titles and abstracts, check full texts for eligibility and perform data extraction. We will resolve dissent by consensus, moderated by a third reviewer. We will include observational and controlled studies addressing target perfusion parameters and outcomes such as survival rates and neurologic findings in OHCA and IHCA patients treated with eCPR. Data extraction tables will be set up, including study and patients’ characteristics, aim of study, details on eCPR including target perfusion parameters and reported outcomes. We will summarise the data using tables and figures (ie, bubble plot) to present the research landscape and to describe potential clusters and/or gaps.Ethics and dissemination An ethical approval is not needed. We intend to publish the scoping review in a peer-reviewed journal and present results on a scientific meeting.https://bmjopen.bmj.com/content/9/8/e030562.full
spellingShingle Lars Saemann
Christine Schmucker
Lisa Rösner
Friedhelm Beyersdorf
Christoph Benk
Perfusion parameters and target values during extracorporeal cardiopulmonary resuscitation: a scoping review protocol
BMJ Open
title Perfusion parameters and target values during extracorporeal cardiopulmonary resuscitation: a scoping review protocol
title_full Perfusion parameters and target values during extracorporeal cardiopulmonary resuscitation: a scoping review protocol
title_fullStr Perfusion parameters and target values during extracorporeal cardiopulmonary resuscitation: a scoping review protocol
title_full_unstemmed Perfusion parameters and target values during extracorporeal cardiopulmonary resuscitation: a scoping review protocol
title_short Perfusion parameters and target values during extracorporeal cardiopulmonary resuscitation: a scoping review protocol
title_sort perfusion parameters and target values during extracorporeal cardiopulmonary resuscitation a scoping review protocol
url https://bmjopen.bmj.com/content/9/8/e030562.full
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