Predictive value of ENLIGHT-DP in patients with metastatic lung adenocarcinoma treated with immune checkpoint inhibitors and platinum chemotherapy directly from histopathology slides using inferred transcriptomics

Predictive value of ENLIGHT-DP in patients with metastatic lung adenocarcinoma treated with immune checkpoint inhibitors and platinum chemotherapy directly from histopathology slides using inferred transcriptomics

Introduction Immune checkpoint inhibitors (ICI) have improved outcomes in non-small cell lung cancer (NSCLC). Nevertheless, the clinical benefit of ICI as monotherapy or in combination with chemotherapy remains widely varied and existing biomarkers have limited predictive value. We present an analys...

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Main Authors: Eli Pikarsky, Anna Elia, Gal Dinstag, Omer Tirosh, Tuvik Beker, Ranit Aharonov, Hovav Nechushtan, Leon Gugel, Yaron Kinar, Michael Tabi, Tzivia Gottlieb, Aron Popovtzer, Johnathan Arnon, Yakir Rottenberg, Philip Blumenfeld
Format: Article
Language:English
Published: BMJ Publishing Group 2025-01-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/1/e010132.full
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