Expression of TGFB3 in Pyogenic Granuloma
Objective: The aim of the study was to determine the expression of TGFB3 in pyogenic granuloma. Material and Methods: Pathologist used a double-headed light microscope to calculate cutoff values for all the antibodies employed in the investigation. Stained slides were thoroughly washed for 4 minute...
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| Format: | Article |
| Language: | English |
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University Library System, University of Pittsburgh
2025-08-01
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| Series: | Dentistry 3000 |
| Subjects: | |
| Online Access: | http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/950 |
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| Summary: | Objective: The aim of the study was to determine the expression of TGFB3 in pyogenic granuloma. Material and Methods: Pathologist used a double-headed light microscope to calculate cutoff values for all the antibodies employed in the investigation. Stained slides were thoroughly washed for 4 minutes with Gill's Hematoxylin Solution, dehydrated, and mounted using DPX mounting solution. Results: Transforming growth factor beta-3 protein expression was measured using immunohistochemistry. In pyogenic granuloma tissues expression, negative scores (0) were found in 4.5 of 16 samples (18.1%), whereas positive values (+) were found in 10 of 16 samples (33.06%). Conclusion: TGFB3 is expressed in most pyogenic granulomas.
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| ISSN: | 2167-8677 |