Lower birth rate, greater female dementia risk: global and regional patterns and public health implications
Aims This study investigates the relationship between national birth rate and female dementia incidence globally, considering demographic and socioeconomic confounders.Materials & methods Data from 204 countries were analyzed using bivariate correlation, partial correlation, principal component...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Future Science OA |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/20565623.2025.2550897 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849224206396424192 |
|---|---|
| author | Wenpeng You |
| author_facet | Wenpeng You |
| author_sort | Wenpeng You |
| collection | DOAJ |
| description | Aims This study investigates the relationship between national birth rate and female dementia incidence globally, considering demographic and socioeconomic confounders.Materials & methods Data from 204 countries were analyzed using bivariate correlation, partial correlation, principal component analysis, and multiple linear regression. Female dementia incidence rate (FDIR) was the dependent variable. Birth rate served as the main predictor, with ageing (life expectancy), genetic predisposition (Biological State Index), economic affluence (GDP PPP), and urban living as confounders.Results Birth rate demonstrated a significant inverse correlation with female dementia incidence (Pearson’s r = −0.772, p < 0.001), remaining robust after adjusting for confounders (partial r = −0.548, p < 0.001). Stepwise regression confirmed birth rate as the strongest independent predictor, explaining 61.6% of the variance in FDIR. Genetic predisposition and ageing were also significant, while economic affluence and urban living had minimal effects. The inverse relationship was more pronounced in developing countries and low-income regions.Conclusions Lower birth rates were strongly associated with higher female dementia incidence globally. Birth rate should be considered a critical demographic factor in dementia risk prediction and public health planning, particularly in ageing and low-resource settings. |
| format | Article |
| id | doaj-art-3ce8fad8ea6c4acdbaaf453a9be89df8 |
| institution | Kabale University |
| issn | 2056-5623 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Future Science OA |
| spelling | doaj-art-3ce8fad8ea6c4acdbaaf453a9be89df82025-08-25T12:43:27ZengTaylor & Francis GroupFuture Science OA2056-56232025-12-0111110.1080/20565623.2025.2550897Lower birth rate, greater female dementia risk: global and regional patterns and public health implicationsWenpeng You0Adelaide Medical School, The University of Adelaide, Adelaide, AustraliaAims This study investigates the relationship between national birth rate and female dementia incidence globally, considering demographic and socioeconomic confounders.Materials & methods Data from 204 countries were analyzed using bivariate correlation, partial correlation, principal component analysis, and multiple linear regression. Female dementia incidence rate (FDIR) was the dependent variable. Birth rate served as the main predictor, with ageing (life expectancy), genetic predisposition (Biological State Index), economic affluence (GDP PPP), and urban living as confounders.Results Birth rate demonstrated a significant inverse correlation with female dementia incidence (Pearson’s r = −0.772, p < 0.001), remaining robust after adjusting for confounders (partial r = −0.548, p < 0.001). Stepwise regression confirmed birth rate as the strongest independent predictor, explaining 61.6% of the variance in FDIR. Genetic predisposition and ageing were also significant, while economic affluence and urban living had minimal effects. The inverse relationship was more pronounced in developing countries and low-income regions.Conclusions Lower birth rates were strongly associated with higher female dementia incidence globally. Birth rate should be considered a critical demographic factor in dementia risk prediction and public health planning, particularly in ageing and low-resource settings.https://www.tandfonline.com/doi/10.1080/20565623.2025.2550897Birth ratefemale dementia incidence ratepredictive influencefamily sizeglobal health |
| spellingShingle | Wenpeng You Lower birth rate, greater female dementia risk: global and regional patterns and public health implications Future Science OA Birth rate female dementia incidence rate predictive influence family size global health |
| title | Lower birth rate, greater female dementia risk: global and regional patterns and public health implications |
| title_full | Lower birth rate, greater female dementia risk: global and regional patterns and public health implications |
| title_fullStr | Lower birth rate, greater female dementia risk: global and regional patterns and public health implications |
| title_full_unstemmed | Lower birth rate, greater female dementia risk: global and regional patterns and public health implications |
| title_short | Lower birth rate, greater female dementia risk: global and regional patterns and public health implications |
| title_sort | lower birth rate greater female dementia risk global and regional patterns and public health implications |
| topic | Birth rate female dementia incidence rate predictive influence family size global health |
| url | https://www.tandfonline.com/doi/10.1080/20565623.2025.2550897 |
| work_keys_str_mv | AT wenpengyou lowerbirthrategreaterfemaledementiariskglobalandregionalpatternsandpublichealthimplications |