Alternative splicing of EZH2 regulated by SNRPB mediates hepatocellular carcinoma progression via BMP2 signaling pathway

Alternative splicing of EZH2 regulated by SNRPB mediates hepatocellular carcinoma progression via BMP2 signaling pathway

Summary: Increasing evidence suggests that aberrant alternative splicing plays crucial roles in tumorigenesis. However, the function of EZH2 splice variants as well as the mechanism by which EZH2 alternative splicing occurs in hepatocellular carcinoma (HCC) remain elusive. Here, we analyzed both our...

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Bibliographic Details
Main Authors: Xingyu Wang, Weiyi Liu, Chunai Zhan, Yuanyuan Zhang, Xinyu Li, Yaoyun Wang, Mengfei Sheng, Madiha Maqsood, Hang Shen, Anmin Liang, Wei Shao
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Molecular mechanism of gene regulation
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224028530
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