Predictors of Preterm Labor: Case-Control Study

Background. The problem of preterm labor is currently the most relevant in modern obstetrics, and therefore requires a comprehensive study and application of an integrated approach to its solution. The identification of risk factors for the development of preterm labor, as well as their complex in a...

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Main Authors: A. V. Sergeeva, O. V. Kovalishena, N. Yu. Katkova, O. I. Bodrikova, I. M. Bezrukova, K. B. Pokusaeva, A. A. Polyakova
Format: Article
Language:Russian
Published: Numikom LLC 2019-06-01
Series:Эпидемиология и вакцинопрофилактика
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Online Access:https://www.epidemvac.ru/jour/article/view/748
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author A. V. Sergeeva
O. V. Kovalishena
N. Yu. Katkova
O. I. Bodrikova
I. M. Bezrukova
K. B. Pokusaeva
A. A. Polyakova
author_facet A. V. Sergeeva
O. V. Kovalishena
N. Yu. Katkova
O. I. Bodrikova
I. M. Bezrukova
K. B. Pokusaeva
A. A. Polyakova
author_sort A. V. Sergeeva
collection DOAJ
description Background. The problem of preterm labor is currently the most relevant in modern obstetrics, and therefore requires a comprehensive study and application of an integrated approach to its solution. The identification of risk factors for the development of preterm labor, as well as their complex in a pregnant woman, makes it possible to attribute them to a high risk group for the development of preterm labor, which further makes t possible to carry out a number of preventive measures.Aims. The purpose of the study was to identify and test the hypothesis of the relationship between various risk factors and the development of preterm labor.Materials and methods. A retrospective descriptive-estimated selective scientific epidemiological study was conducted according tostatistical reporting forms for the period from 2012 to 2016. The study of the causal relationship of risk factors with the occurrence of preterm labor was carried out using a casecontrol analytical study and calculating the odds ratio (OR) with 95% confidence intervals (CI) using the «Epi InfoTM» program.Results and conclusions. The study period was characterized by minor changes in the rate of preterm labor in the Nizhny Novgorod region. The average long-term figure was 5.0%. The level of preterm birth in the Nizhny Novgorod region was 1.3 times higher than in the Russian Federation. The role of the following risk factors in the occurrence of preterm labor was revealed: a history of 2 or more medical abortions (OR 5.09), inflammatory diseases of the pelvic organs (OR 3.15), menstrual disorders (OR 3.38), and arterial hypertension (OR 2,4), MARS (OR 2,07), varicose veins disease (OR 3,08), cervico-vaginal infection (OR 5,33), other infectious and inflammatory diseases (OR 9,2).
format Article
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institution Kabale University
issn 2073-3046
2619-0494
language Russian
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series Эпидемиология и вакцинопрофилактика
spelling doaj-art-3caea2f19ef54788ad98f7a1df82749c2025-08-20T03:57:18ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942019-06-011839810410.31631/2073-3046-2019-18-3-98-104546Predictors of Preterm Labor: Case-Control StudyA. V. Sergeeva0O. V. Kovalishena1N. Yu. Katkova2O. I. Bodrikova3I. M. Bezrukova4K. B. Pokusaeva5A. A. Polyakova6Privolzhskiy Research Medical UniversityPrivolzhskiy Research Medical UniversityPrivolzhskiy Research Medical UniversityPrivolzhskiy Research Medical University; Dzerzhinsky Perinatal CenterPrivolzhskiy Research Medical University; Dzerzhinsky Perinatal CenterPrivolzhskiy Research Medical University; Dzerzhinsky Perinatal CenterPrivolzhskiy Research Medical UniversityBackground. The problem of preterm labor is currently the most relevant in modern obstetrics, and therefore requires a comprehensive study and application of an integrated approach to its solution. The identification of risk factors for the development of preterm labor, as well as their complex in a pregnant woman, makes it possible to attribute them to a high risk group for the development of preterm labor, which further makes t possible to carry out a number of preventive measures.Aims. The purpose of the study was to identify and test the hypothesis of the relationship between various risk factors and the development of preterm labor.Materials and methods. A retrospective descriptive-estimated selective scientific epidemiological study was conducted according tostatistical reporting forms for the period from 2012 to 2016. The study of the causal relationship of risk factors with the occurrence of preterm labor was carried out using a casecontrol analytical study and calculating the odds ratio (OR) with 95% confidence intervals (CI) using the «Epi InfoTM» program.Results and conclusions. The study period was characterized by minor changes in the rate of preterm labor in the Nizhny Novgorod region. The average long-term figure was 5.0%. The level of preterm birth in the Nizhny Novgorod region was 1.3 times higher than in the Russian Federation. The role of the following risk factors in the occurrence of preterm labor was revealed: a history of 2 or more medical abortions (OR 5.09), inflammatory diseases of the pelvic organs (OR 3.15), menstrual disorders (OR 3.38), and arterial hypertension (OR 2,4), MARS (OR 2,07), varicose veins disease (OR 3,08), cervico-vaginal infection (OR 5,33), other infectious and inflammatory diseases (OR 9,2).https://www.epidemvac.ru/jour/article/view/748preterm laborrisk factorsodds ratioanalytical studiescase-control study
spellingShingle A. V. Sergeeva
O. V. Kovalishena
N. Yu. Katkova
O. I. Bodrikova
I. M. Bezrukova
K. B. Pokusaeva
A. A. Polyakova
Predictors of Preterm Labor: Case-Control Study
Эпидемиология и вакцинопрофилактика
preterm labor
risk factors
odds ratio
analytical studies
case-control study
title Predictors of Preterm Labor: Case-Control Study
title_full Predictors of Preterm Labor: Case-Control Study
title_fullStr Predictors of Preterm Labor: Case-Control Study
title_full_unstemmed Predictors of Preterm Labor: Case-Control Study
title_short Predictors of Preterm Labor: Case-Control Study
title_sort predictors of preterm labor case control study
topic preterm labor
risk factors
odds ratio
analytical studies
case-control study
url https://www.epidemvac.ru/jour/article/view/748
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AT ovkovalishena predictorsofpretermlaborcasecontrolstudy
AT nyukatkova predictorsofpretermlaborcasecontrolstudy
AT oibodrikova predictorsofpretermlaborcasecontrolstudy
AT imbezrukova predictorsofpretermlaborcasecontrolstudy
AT kbpokusaeva predictorsofpretermlaborcasecontrolstudy
AT aapolyakova predictorsofpretermlaborcasecontrolstudy