Novel sulphur-selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruits

Thiram (THI) and asomate (ASO) are frequently detected agrochemicals in food samples due to widespread use as fungicides. However, their detection suffers from matrix interference, or the necessity of derivatization before measurement. Integrating HPLC with a post-column carbon dots (CDs)–enhanced c...

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Main Authors: Lijun Wei, Mengdie Cai, Bixiao Zhou, Ping Yuan, Guowen Zhang, Xianglei Cheng
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Food Chemistry: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590157524007673
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author Lijun Wei
Mengdie Cai
Bixiao Zhou
Ping Yuan
Guowen Zhang
Xianglei Cheng
author_facet Lijun Wei
Mengdie Cai
Bixiao Zhou
Ping Yuan
Guowen Zhang
Xianglei Cheng
author_sort Lijun Wei
collection DOAJ
description Thiram (THI) and asomate (ASO) are frequently detected agrochemicals in food samples due to widespread use as fungicides. However, their detection suffers from matrix interference, or the necessity of derivatization before measurement. Integrating HPLC with a post-column carbon dots (CDs)–enhanced chemiluminescence (CL) system makes it possible to simultaneously separate and selectively detect ASO and THI in fruit samples free of derivatization and deep purification. The studies on mechanisms demonstrated that CD intermediates of anionic radical were responsible for the remarkable CL enhancement of ASO or THI. The CL intensity is directly proportional to the fungicide concentration, with the ranges of linearity for ASO and THI being 5–250 μg·L−1 (R2 = 0.9993) and 4–200 μg·L−1 (R2 = 0.9986), respectively, and the corresponding limits of detection (S/N = 3) being 1.61 and 1.33 μg·L−1, respectively. The developed method enables the exploration of the novelly sulphur-targeted CL application based on carbon nanomaterials.
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id doaj-art-3c8cf9b24ceb460c9044036b12cd8e6f
institution Kabale University
issn 2590-1575
language English
publishDate 2024-12-01
publisher Elsevier
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series Food Chemistry: X
spelling doaj-art-3c8cf9b24ceb460c9044036b12cd8e6f2024-12-13T11:01:38ZengElsevierFood Chemistry: X2590-15752024-12-0124101879Novel sulphur-selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruitsLijun Wei0Mengdie Cai1Bixiao Zhou2Ping Yuan3Guowen Zhang4Xianglei Cheng5State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, PR China; Jiangxi Province Key Laboratory of Disease Prevention and Public Health, School of Public Health, Jiangxi Medical College, Nanchang University, Nanchang 330006, PR ChinaJiangxi Province Key Laboratory of Disease Prevention and Public Health, School of Public Health, Jiangxi Medical College, Nanchang University, Nanchang 330006, PR ChinaJiangxi Province Key Laboratory of Disease Prevention and Public Health, School of Public Health, Jiangxi Medical College, Nanchang University, Nanchang 330006, PR ChinaJiangxi Province Key Laboratory of Disease Prevention and Public Health, School of Public Health, Jiangxi Medical College, Nanchang University, Nanchang 330006, PR ChinaState Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, PR China; Corresponding author at: State Key Laboratory of Food Science and Resources, Nanchang University, 235 Nanjing East Road, Nanchang city, Jiangxi province 330047, PR China.Jiangxi Province Key Laboratory of Disease Prevention and Public Health, School of Public Health, Jiangxi Medical College, Nanchang University, Nanchang 330006, PR China; Corresponding author at: School of Public Health, Nanchang University, 461 Bayi Road, Nanchang 330006, PR China.Thiram (THI) and asomate (ASO) are frequently detected agrochemicals in food samples due to widespread use as fungicides. However, their detection suffers from matrix interference, or the necessity of derivatization before measurement. Integrating HPLC with a post-column carbon dots (CDs)–enhanced chemiluminescence (CL) system makes it possible to simultaneously separate and selectively detect ASO and THI in fruit samples free of derivatization and deep purification. The studies on mechanisms demonstrated that CD intermediates of anionic radical were responsible for the remarkable CL enhancement of ASO or THI. The CL intensity is directly proportional to the fungicide concentration, with the ranges of linearity for ASO and THI being 5–250 μg·L−1 (R2 = 0.9993) and 4–200 μg·L−1 (R2 = 0.9986), respectively, and the corresponding limits of detection (S/N = 3) being 1.61 and 1.33 μg·L−1, respectively. The developed method enables the exploration of the novelly sulphur-targeted CL application based on carbon nanomaterials.http://www.sciencedirect.com/science/article/pii/S2590157524007673ThiramAsomateN-doped carbon dotsSulphur-selective chemiluminescence
spellingShingle Lijun Wei
Mengdie Cai
Bixiao Zhou
Ping Yuan
Guowen Zhang
Xianglei Cheng
Novel sulphur-selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruits
Food Chemistry: X
Thiram
Asomate
N-doped carbon dots
Sulphur-selective chemiluminescence
title Novel sulphur-selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruits
title_full Novel sulphur-selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruits
title_fullStr Novel sulphur-selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruits
title_full_unstemmed Novel sulphur-selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruits
title_short Novel sulphur-selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruits
title_sort novel sulphur selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruits
topic Thiram
Asomate
N-doped carbon dots
Sulphur-selective chemiluminescence
url http://www.sciencedirect.com/science/article/pii/S2590157524007673
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