Antimicrobial Properties of Monomeric and Dimeric Catanionic Surfactant System
Cationic gemini surfactants are used due to their broad spectrum of activity, especially surface, anticorrosive and antimicrobial properties. Mixtures of cationic and anionic surfactants are also increasingly described. In order to investigate the effect of anionic additive on antimicrobial activity...
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MDPI AG
2025-01-01
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| Series: | Molecules |
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| author | Iwona Kowalczyk Anna Koziróg Adrianna Szulc Anna Komasa Bogumił Brycki |
| author_facet | Iwona Kowalczyk Anna Koziróg Adrianna Szulc Anna Komasa Bogumił Brycki |
| author_sort | Iwona Kowalczyk |
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| description | Cationic gemini surfactants are used due to their broad spectrum of activity, especially surface, anticorrosive and antimicrobial properties. Mixtures of cationic and anionic surfactants are also increasingly described. In order to investigate the effect of anionic additive on antimicrobial activity, experimental studies were carried out to obtain MIC (minimal inhibitory concentration) against <i>E. coli</i> and <i>S. aureus</i> bacteria. Two gemini surfactants (12-6-12 and 12-O-12) and two single quaternary ammonium salts (DTAB and DDAC) were analyzed. The most commonly used commercial compounds of this class, i.e., SDS and SL, were used as anionic additives. In addition, computer quantum mechanical studies were also carried out to confirm the relationship between the structure of the mixture and the activity. The obtained results of microbiological tests and quantum mechanical calculations are in agreement with each other and show the lack of synergism in catanionic mixtures in the case of antibacterial activity. |
| format | Article |
| id | doaj-art-3c5fb08bd17549c3afe3b6f7b3a12b4b |
| institution | Kabale University |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
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| series | Molecules |
| spelling | doaj-art-3c5fb08bd17549c3afe3b6f7b3a12b4b2025-01-10T13:19:05ZengMDPI AGMolecules1420-30492025-01-0130116410.3390/molecules30010164Antimicrobial Properties of Monomeric and Dimeric Catanionic Surfactant SystemIwona Kowalczyk0Anna Koziróg1Adrianna Szulc2Anna Komasa3Bogumił Brycki4Department of Bioactive Products, Faculty of Chemistry, Adam Mickiewicz University Poznan, 61-614 Poznan, PolandInstitute of Fermentation Technology and Microbiology, Faculty of Biotechnology and Food Science, Lodz University of Technology, 90-924 Lodz, PolandDepartment of Bioactive Products, Faculty of Chemistry, Adam Mickiewicz University Poznan, 61-614 Poznan, PolandDepartment of Bioactive Products, Faculty of Chemistry, Adam Mickiewicz University Poznan, 61-614 Poznan, PolandDepartment of Bioactive Products, Faculty of Chemistry, Adam Mickiewicz University Poznan, 61-614 Poznan, PolandCationic gemini surfactants are used due to their broad spectrum of activity, especially surface, anticorrosive and antimicrobial properties. Mixtures of cationic and anionic surfactants are also increasingly described. In order to investigate the effect of anionic additive on antimicrobial activity, experimental studies were carried out to obtain MIC (minimal inhibitory concentration) against <i>E. coli</i> and <i>S. aureus</i> bacteria. Two gemini surfactants (12-6-12 and 12-O-12) and two single quaternary ammonium salts (DTAB and DDAC) were analyzed. The most commonly used commercial compounds of this class, i.e., SDS and SL, were used as anionic additives. In addition, computer quantum mechanical studies were also carried out to confirm the relationship between the structure of the mixture and the activity. The obtained results of microbiological tests and quantum mechanical calculations are in agreement with each other and show the lack of synergism in catanionic mixtures in the case of antibacterial activity.https://www.mdpi.com/1420-3049/30/1/164catanionic surfactant systemantibacterial activityDFT calculations |
| spellingShingle | Iwona Kowalczyk Anna Koziróg Adrianna Szulc Anna Komasa Bogumił Brycki Antimicrobial Properties of Monomeric and Dimeric Catanionic Surfactant System Molecules catanionic surfactant system antibacterial activity DFT calculations |
| title | Antimicrobial Properties of Monomeric and Dimeric Catanionic Surfactant System |
| title_full | Antimicrobial Properties of Monomeric and Dimeric Catanionic Surfactant System |
| title_fullStr | Antimicrobial Properties of Monomeric and Dimeric Catanionic Surfactant System |
| title_full_unstemmed | Antimicrobial Properties of Monomeric and Dimeric Catanionic Surfactant System |
| title_short | Antimicrobial Properties of Monomeric and Dimeric Catanionic Surfactant System |
| title_sort | antimicrobial properties of monomeric and dimeric catanionic surfactant system |
| topic | catanionic surfactant system antibacterial activity DFT calculations |
| url | https://www.mdpi.com/1420-3049/30/1/164 |
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