Radiofrequency ablation for papillary thyroid microcarcinoma with a trachea-adjacent versus trachea-distant location
Objective To evaluate the outcomes of radiofrequency ablation (RFA) for papillary thyroid microcarcinoma (PTMC) adjacent to the trachea and compare them with those of PTMC distant from the trachea.Methods Patients who received RFA for solitary low-risk PTMC between June 2014 and July 2020 were revie...
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Taylor & Francis Group
2024-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2023.2270671 |
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| author | Haoyu Jing Lin Yan Jing Xiao Xinyang Li Bo Jiang Zhen Yang Yingying Li Bin Sun Mingbo Zhang Yukun Luo |
| author_facet | Haoyu Jing Lin Yan Jing Xiao Xinyang Li Bo Jiang Zhen Yang Yingying Li Bin Sun Mingbo Zhang Yukun Luo |
| author_sort | Haoyu Jing |
| collection | DOAJ |
| description | Objective To evaluate the outcomes of radiofrequency ablation (RFA) for papillary thyroid microcarcinoma (PTMC) adjacent to the trachea and compare them with those of PTMC distant from the trachea.Methods Patients who received RFA for solitary low-risk PTMC between June 2014 and July 2020 were reviewed and classified into adjacent and distant groups. To balance between-group confounders, the propensity score matching approach was employed. Volume, volume reduction ratio (VRR), tumor disappearance, complications, and disease progression were assessed and compared between the groups. Furthermore, factors affecting disease progression were evaluated.Results A total of 122 and 470 patients were included in the adjacent and distant groups, respectively. Overall VRR was 99.5% ± 3.1 and cumulative tumor disappearance rate was 99.4% after a mean follow-up time of 40.1 months ± 16.2. Overall disease progression and complications incidence were 3.7% and 1.0%, respectively. No substantial differences were observed between the two groups in the latest volume (0.8 mm3 ± 4.1 vs. 0.9 mm3 ± 4.2, p = .77), VRR (99.7% ± 1.6 vs. 99.5% ± 2.7, p = .75), cumulative tumor disappearance rate (92.6% vs. 94.2%, p = .58), and incidence of disease progression (4.1% vs. 4.5%, p = .70) and complication (1.7% vs. 0.8%, p = .86) after 1:2 matching. Additionally, tracheal adjacency exhibited no association with disease progression in multivariate Cox regression analysis (p = .73).Conclusion For eligible patients with PTMC located adjacent to or distant from the trachea, RFA may offer a safe and effective alternative treatment method. |
| format | Article |
| id | doaj-art-3bfa006caf3a4d2c9a9d66151b611d6a |
| institution | Kabale University |
| issn | 0265-6736 1464-5157 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj-art-3bfa006caf3a4d2c9a9d66151b611d6a2025-01-03T09:30:28ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572024-12-0141110.1080/02656736.2023.2270671Radiofrequency ablation for papillary thyroid microcarcinoma with a trachea-adjacent versus trachea-distant locationHaoyu Jing0Lin Yan1Jing Xiao2Xinyang Li3Bo Jiang4Zhen Yang5Yingying Li6Bin Sun7Mingbo Zhang8Yukun Luo9Chinese PLA Medical School, Beijing, ChinaDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaChinese PLA Medical School, Beijing, ChinaDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Ultrasound, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaObjective To evaluate the outcomes of radiofrequency ablation (RFA) for papillary thyroid microcarcinoma (PTMC) adjacent to the trachea and compare them with those of PTMC distant from the trachea.Methods Patients who received RFA for solitary low-risk PTMC between June 2014 and July 2020 were reviewed and classified into adjacent and distant groups. To balance between-group confounders, the propensity score matching approach was employed. Volume, volume reduction ratio (VRR), tumor disappearance, complications, and disease progression were assessed and compared between the groups. Furthermore, factors affecting disease progression were evaluated.Results A total of 122 and 470 patients were included in the adjacent and distant groups, respectively. Overall VRR was 99.5% ± 3.1 and cumulative tumor disappearance rate was 99.4% after a mean follow-up time of 40.1 months ± 16.2. Overall disease progression and complications incidence were 3.7% and 1.0%, respectively. No substantial differences were observed between the two groups in the latest volume (0.8 mm3 ± 4.1 vs. 0.9 mm3 ± 4.2, p = .77), VRR (99.7% ± 1.6 vs. 99.5% ± 2.7, p = .75), cumulative tumor disappearance rate (92.6% vs. 94.2%, p = .58), and incidence of disease progression (4.1% vs. 4.5%, p = .70) and complication (1.7% vs. 0.8%, p = .86) after 1:2 matching. Additionally, tracheal adjacency exhibited no association with disease progression in multivariate Cox regression analysis (p = .73).Conclusion For eligible patients with PTMC located adjacent to or distant from the trachea, RFA may offer a safe and effective alternative treatment method.https://www.tandfonline.com/doi/10.1080/02656736.2023.2270671Ablation techniquesradiofrequency ablationpapillary thyroid microcarcinomaultrasonography |
| spellingShingle | Haoyu Jing Lin Yan Jing Xiao Xinyang Li Bo Jiang Zhen Yang Yingying Li Bin Sun Mingbo Zhang Yukun Luo Radiofrequency ablation for papillary thyroid microcarcinoma with a trachea-adjacent versus trachea-distant location International Journal of Hyperthermia Ablation techniques radiofrequency ablation papillary thyroid microcarcinoma ultrasonography |
| title | Radiofrequency ablation for papillary thyroid microcarcinoma with a trachea-adjacent versus trachea-distant location |
| title_full | Radiofrequency ablation for papillary thyroid microcarcinoma with a trachea-adjacent versus trachea-distant location |
| title_fullStr | Radiofrequency ablation for papillary thyroid microcarcinoma with a trachea-adjacent versus trachea-distant location |
| title_full_unstemmed | Radiofrequency ablation for papillary thyroid microcarcinoma with a trachea-adjacent versus trachea-distant location |
| title_short | Radiofrequency ablation for papillary thyroid microcarcinoma with a trachea-adjacent versus trachea-distant location |
| title_sort | radiofrequency ablation for papillary thyroid microcarcinoma with a trachea adjacent versus trachea distant location |
| topic | Ablation techniques radiofrequency ablation papillary thyroid microcarcinoma ultrasonography |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2023.2270671 |
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