Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective study
Introduction Multimorbidity, the co-occurrence of a chronic physical condition and mental disorder, affects a substantial number of children and youth and can lead to compromised quality of life, hardship for families, and an increased burden on the healthcare system. We are conducting a study to do...
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BMJ Publishing Group
2019-11-01
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| author | Michael Boyle Mark A Ferro Brian Timmons Ellen L Lipman Ryan J Van Lieshout Jan Willem Gorter Lilly Shanahan Kathy Georgiades |
| author_facet | Michael Boyle Mark A Ferro Brian Timmons Ellen L Lipman Ryan J Van Lieshout Jan Willem Gorter Lilly Shanahan Kathy Georgiades |
| author_sort | Michael Boyle |
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| description | Introduction Multimorbidity, the co-occurrence of a chronic physical condition and mental disorder, affects a substantial number of children and youth and can lead to compromised quality of life, hardship for families, and an increased burden on the healthcare system. We are conducting a study to document the course of mental disorder in children and youth diagnosed with a chronic physical condition; identify predictors of child and youth multimorbidity; examine whether the effects of these predictors are moderated by relevant psychosocial and biological factors; explore potential inflammatory and stress biomarkers that mediate the onset of child and youth multimorbidity; and, assess whether multimorbidity in children and youth alters patterns of mental health service use.Methods and analysis Multimorbidity in Children and Youth Across the Life-course (MY LIFE) is a prospective study. Two hundred and fifty children and youth aged 2–16 years diagnosed with a chronic physical condition along with one parent will be recruited from the outpatient clinics at a paediatric tertiary care centre. Data will be collected using a multi-informant, multimethod design at four time-points (at recruitment, and at 6, 12 and 24 months postrecruitment). Parents will provide reports for all children/youth. In addition, youth ≥10 years will self-report. Mental disorder will be assessed using structured interviews. On completion of data collection, participant-reported data will be linked to provincial health records to identify mental health services use. Multilevel analyses (survival, proportional hazard, structural equation modelling) will be used to address MY LIFE objectives.Ethics and dissemination This study has been approved by the University of Waterloo Human Research Ethics Board and the Hamilton Integrated Research Ethics Board. Findings will be disseminated to key stakeholders using a number of outlets (peer-reviewed publications and conferences, lay informational pamphlets, social media). |
| format | Article |
| id | doaj-art-3be844b793384e31883cfd557de3d3c5 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2019-11-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-3be844b793384e31883cfd557de3d3c52024-11-29T17:50:12ZengBMJ Publishing GroupBMJ Open2044-60552019-11-0191110.1136/bmjopen-2019-034544Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective studyMichael Boyle0Mark A Ferro1Brian Timmons2Ellen L Lipman3Ryan J Van Lieshout4Jan Willem Gorter5Lilly Shanahan6Kathy Georgiades7Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, CanadaSchool of Public Health and Health Systems, University of Waterloo, Waterloo, Ontario, CanadaDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, CanadaDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, CanadaDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, CanadaCanChild Centre for Childhood Disability Research, Department of Pediatrics, McMaster University, Hamilton, Ontario, CanadaDepartment of Psychology, University of Zurich, Zurich, Switzerland1 Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, CanadaIntroduction Multimorbidity, the co-occurrence of a chronic physical condition and mental disorder, affects a substantial number of children and youth and can lead to compromised quality of life, hardship for families, and an increased burden on the healthcare system. We are conducting a study to document the course of mental disorder in children and youth diagnosed with a chronic physical condition; identify predictors of child and youth multimorbidity; examine whether the effects of these predictors are moderated by relevant psychosocial and biological factors; explore potential inflammatory and stress biomarkers that mediate the onset of child and youth multimorbidity; and, assess whether multimorbidity in children and youth alters patterns of mental health service use.Methods and analysis Multimorbidity in Children and Youth Across the Life-course (MY LIFE) is a prospective study. Two hundred and fifty children and youth aged 2–16 years diagnosed with a chronic physical condition along with one parent will be recruited from the outpatient clinics at a paediatric tertiary care centre. Data will be collected using a multi-informant, multimethod design at four time-points (at recruitment, and at 6, 12 and 24 months postrecruitment). Parents will provide reports for all children/youth. In addition, youth ≥10 years will self-report. Mental disorder will be assessed using structured interviews. On completion of data collection, participant-reported data will be linked to provincial health records to identify mental health services use. Multilevel analyses (survival, proportional hazard, structural equation modelling) will be used to address MY LIFE objectives.Ethics and dissemination This study has been approved by the University of Waterloo Human Research Ethics Board and the Hamilton Integrated Research Ethics Board. Findings will be disseminated to key stakeholders using a number of outlets (peer-reviewed publications and conferences, lay informational pamphlets, social media).https://bmjopen.bmj.com/content/9/11/e034544.full |
| spellingShingle | Michael Boyle Mark A Ferro Brian Timmons Ellen L Lipman Ryan J Van Lieshout Jan Willem Gorter Lilly Shanahan Kathy Georgiades Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective study BMJ Open |
| title | Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective study |
| title_full | Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective study |
| title_fullStr | Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective study |
| title_full_unstemmed | Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective study |
| title_short | Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective study |
| title_sort | multimorbidity in children and youth across the life course my life protocol of a canadian prospective study |
| url | https://bmjopen.bmj.com/content/9/11/e034544.full |
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