Expression of pyrethroid metabolizing P450 enzymes characterizes highly resistant Anopheles vector species targeted by successful deployment of PBO-treated bednets in Tanzania.

Expression of pyrethroid metabolizing P450 enzymes characterizes highly resistant Anopheles vector species targeted by successful deployment of PBO-treated bednets in Tanzania.

Long lasting insecticidal nets (LLINs) are a proven tool to reduce malaria transmission, but in Africa efficacy is being reduced by pyrethroid resistance in the major vectors. A previous study that was conducted in Muleba district, Tanzania indicated possible involvement of cytochrome P450 monooxyge...

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Main Authors: Johnson Matowo, David Weetman, Patricia Pignatelli, Alexandra Wright, Jacques D Charlwood, Robert Kaaya, Boniface Shirima, Oliva Moshi, Eliud Lukole, Jacklin Mosha, Alphaxard Manjurano, Franklin Mosha, Mark Rowland, Natacha Protopopoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0249440&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0249440&type=printable

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